Vitrakvi 100mg Capsule (Larotrectinib)
Prescription RequiredManufactured By
Alleviare
Pack Of
60
Salt Composition
Larotrectinib
Storage
Keep in cold place
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ALL SUBSTITUTES
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Vitrakvi 25mg Capsule
Overview
Vitrakvi 100mg Capsule is a prescription based anticancer medicine. It is used to treat solid tumors in adult and paediatric patients with Neurotrophic Tyrosine Receptor Kinase (NTRK) gene fusion.
It contains Larotrectinib as an active ingredient which belongs to a drug of class known as tyrosine kinase inhibitor (TKI). It works by blocking the action of specific protein that regulate cancer cell growth.
Indication
Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer
Side Effects
Every medicine has some side effects that manage on their own as your body gets used to the medicine, but some people may rarely experience severe side effects. In that case, the patient should contact the doctor immediately.
Some common side effects of Vitrakvi 100mg Capsule(Larotrectinib 100mg) include:
● Fatigue or tiredness
● Nausea and vomiting
● Dizziness
● Cough
● Constipation or diarrhea
● Abnormal liver function tests (increased AST and ALT)
● Musculoskeletal (muscle, bone, or joint) pain
● Fever
● Anemia (low red blood cell count)
● Weight gain
● Decreased appetite
Seek medical attention in case of any unusual or severe side effects immediately.
How To Use
Doctor determines the dosage and duration of Vitrakvi 100mg Capsule(Larotrectinib 100mg) as per the type of disease and overall health condition of the patients. Do not crush or break the tablet. This tablet may be taken with or without food. In case of an overdose, the doctor will provide emergency medical treatment. Do not stop or change the dose without informing your doctor.
Reference
● Ricciuti, B., Genova, C., Crinò, L., Libra, M., & Leonardi, G. C. (2019). Antitumor activity of larotrectinib in tumors harboring NTRK gene fusions: a short review on the current evidence. OncoTargets and therapy, 3171-3179.
● Scott, L. J. (2019). Larotrectinib: first global approval. Drugs, 79(2), 201-206.
● Raedler, L. A. (2019). Vitrakvi (Larotrectinib) First TRK Inhibitor Approved by the FDA for Solid Tumors Based on a Genetic Mutation.
● Bernsen, E. C., Hogenes, V. J., Nuijen, B., Hanff, L. M., Huitema, A. D., & Diekstra, M. H. (2022). Practical recommendations for the manipulation of kinase inhibitor formulations to age-appropriate dosage forms. Pharmaceutics, 14(12), 2834.
● Team, R. (2021). Larotrectinib (Vitrakvi). Canadian Journal of Health Technologies, 1(11).
Safety Advice
- ● Alcohol: Avoid the consumption of alcohol while taking Vitrakvi 100mg Capsule, as alcohol can reduce the effectiveness of the medicine and worsen the symptoms.
- ● Pregnancy: Vitrakvi 100mg Capsule(Larotrectinib 100mg) is not recommended during pregnancy as it is unsafe for the developing fetus. Doctors rarely prescribe this medicine in pregnancy.
- ● Breastfeeding: Vitrakvi 100mg Capsule is unsafe to use during breastfeeding as it may cause toxicity to the baby.
- ● Driving: Vitrakvi 100mg Capsule(Larotrectinib 100mg) may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving or operating heavy machinery.
- ● Kidney: Consumption of Vitrakvi 100mg Capsule should be avoided without informing the doctor if you have any kidney-related issues.
- ● Liver: Consumption of Vitrakvi 100mg Capsule(Larotrectinib 100mg) should be avoided without informing the doctor if you have any liver-related issues.
FAQs
What are the side effects of taking Vitrakvi 100mg Capsule?
Like any other anticancer medicine Vitrakvi 100mg Capsule(Larotrectinib) also shows some side effects like fatigue, tiredness, nausea, vomiting, dizziness, cough, constipation or diarrhea.
When should be Vitrakvi 100mg Capsule(Larotrectinib 100mg) prescribes?
Doctor prescribes Vitrakvi 100mg to treat solid tumors in patients with Neurotrophic Tyrosine Receptor Kinase (NTRK) gene fusion.
Can a woman take this capsule while breastfeeding?
Try to avoid breastfeed while taking Vitrakvi at least for one week after your last dose.
How to store Vitrakvi 100mg?
Vitrakvi capsule(Larotrectinib 100mg) should be stored at room temperature usually between 68 F and 77 F (20 C and 25 C). Vitrakvi capsule(Larotrectinib 100mg) should be stored at room temperature usually between 68 F and 77 F (20 C and 25 C).
What is the active ingredient of Vitrakvi 100mg?
The active ingredient of Vitrakvi 100mg is Larotrectinib.
Marketer Details
Alleviare
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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