Xeljanz 5mg Tablet (Tofacitinib)
Prescription RequiredManufactured By
Pfizer
Pack Of
60
Salt Composition
Tofacitinib
Storage
Keep in cold place
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Overview
Xeljanz 5mg Tablet is a prescription-based medicine used in the treatment of severe rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. It contains tofacitinib as an active ingredient that belongs to the class of medications known as Janus kinase inhibitors. Xeljanz works by blocking JAK enzymes involved in immune-system signaling. This helps to decrease pain, tenderness, and swelling in the joints by reducing inflammation. This tofacitinib 5mg tablet also helps to slow down the progression of bone and joint damage. It can be prescribed alone or in combination with other medicines.
The tablet is taken orally and exactly as prescribed by the doctor. The tablet must be swallowed as whole with water and should not be crushed, chewed, or broken. It is usually taken with or without food. The tofacitinib 5mg tablet is given twice daily, and a doctor decides the dose and timings according to the patient's condition, combination therapy and clinical response. Patients are advised not to change the dosage because it can lead to severe side effects.
Common side effects include headache, diarrhea, nausea, increased cholesterol levels, upper respiratory tract infections and sore throat. A few patients can undergo severe side effects, including serious infections, blood clots, heart attack or stroke, certain cancers, and significant changes in blood cell counts. Most of the tofacitinib 5mg tablet side effects can leave when the body adapts to the medicine. However, if any side effects persist, inform your doctor immediately.
The medicine may cause harm to an unborn baby, and pregnant women must stop using it. Avoid live vaccines and use effective contraception during treatment. Patients must list all medicines, supplements, and herbal products that they are taking. The tofacitinib 5mg tablet must be used under medical oversight or medical supervision only. Attend regular tests and follow-ups to monitor the medicine response and reduce side effects. Before making any adjustments, changing the dose, or stopping the treatment, consult with your doctor to maximize the benefit.
Indication
Rheumatology and Gastroenterology
Side Effects
Side effects are undesirable symptoms that can result from any medical treatment. Like any other medicine, Xeljanz 5mg Tablet (Tofacitinib 5mg) also causes some adverse impact on the body, most of which resolve without any medical attention. Seek medical attention in case of any unusual or severe side effects immediately.
Some common side effects include:
● Headache
● Upper respiratory tract infection
● Diarrhea
● Nasopharyngitis (inflammation of the throat and nasal passages)
● High blood pressure
● Elevated cholestrol levels
● Acne
● Rash
How To Use
The doctor determines the dosage and duration of the Xeljanz 5mg Tablet (Tofacitinib 5mg) as per the type of disease and overall health condition of the patients. Swallow it as a whole with water. Do not chew, crush or break it. This tablet may be taken with or without food. In case of an overdose of this tablet, contact your doctor or any healthcare provider and seek medical attention immediately.
Reference
● Raedler, L. A. (2017). Xeljanz XR (Tofacitinib) First Once-Daily Oral JAK Inhibitor Approved for Patients with Rheumatoid Arthritis.
● Scott, L. J. (2013). Tofacitinib: a review of its use in adult patients with rheumatoid arthritis. Drugs, 73(8), 857-874.
● Sandborn, W. J., Su, C., Sands, B. E., D’Haens, G. R., Vermeire, S., Schreiber, S., ... & Panés, J. (2017). Tofacitinib as induction and maintenance therapy for ulcerative colitis. New England Journal of Medicine, 376(18), 1723-1736.
● Lee, E. B., Fleischmann, R., Hall, S., Wilkinson, B., Bradley, J. D., Gruben, D., ... & Van Vollenhoven, R. F. (2014). Tofacitinib versus methotrexate in rheumatoid arthritis. New England Journal of Medicine, 370(25), 2377-2386.
● He, Y., Wong, A. Y., Chan, E. W., Lau, W. C., Man, K. K., Chui, C. S., ... & Wong, I. C. (2013). Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis. BMC musculoskeletal disorders, 14(1), 298.
Safety Advice
- ● Alcohol: Avoid the consumption of alcohol while taking Xeljanz 5mg Tablet (Tofacitinib 5mg), as alcohol can increase liver damage, which reduces the effectiveness of the medicine and worsens the symptoms.
- ● Pregnancy: Do not take the Xeljanz 5mg Tablet without consulting the doctor in case of pregnancy, as it is an unsafe medicine during this period.
- ● Breastfeeding: Xeljanz 5mg Tablet (Tofacitinib 5mg) is unsafe to use during breastfeeding, as it may cause toxicity to the baby.
- ● Driving: Xeljanz 5mg Tablet is usually considered safe in case of driving, as it does not affect your ability to drive.
- ● Kidney: Consumption of Xeljanz 5mg Tablet (Tofacitinib 5mg) should be avoided without informing the doctor if you have any kidney-related issues.
- ● Liver: Consumption of Xeljanz 5mg Tablet should be avoided without informing the doctor if you have any liver-related issues.
FAQs
What are the uses of Xeljanz 5mg Tablet(Tofacitinib 5mg)?
This is a prescription based medicine used in the treatment of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis.
What are the side effects of taking Xeljanz 5mg Tablet?
Some common side effects of taking Xeljanz(Tofacitinib 5mg) include headache, upper respiratory tract infection, diarrhea, etc.
How to take Xeljanz 5mg Tablet?
Take Xeljanz 5mg Tablet(Tofacitinib 5mg) as advice by the doctor on a fix time everyday to get a better result. Also swallow the tablet as a whole with water.
How does Xeljanz 5mg Tablet works?
Xeljanz 5mg Tablet(Tofacitinib 5mg) is belongs to class of drug known as Janus kinase inhibitor the works by blocking the action of the enzyme known as Janus kinase and reduce the inflammation and pain of the joints.
Is consumption of Xeljanz 5mg Tablet safe during driving?
Yes, it is consider to be safe because Xeljanz(Tofacitinib 5mg tablet) does not usually affects the ability of drive.
Marketer Details
Pfizer
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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