

Glivec 400mg Tablet (Imatinib)
Manufactured By
Novartis
Pack Of
30
Salt Composition
Imatinib
Storage
Keep in cold place
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Overview
Glivec 400mg Tablet is an anticancer medicine which is used in chronic myeloid leukemia & acute lymphocytic leukemia and gastrointestinal stromal tumors. It contains an active ingredient known as imatinib. It works by inhibiting the specific proteins called tyrosine kinases that promote the growth and multiplication of cancer cells. This can stop the cancer progression and cancer load inside the body. Imatinib 400mg Tablet can also be used to treat a skin tumor called dermatofibrosarcoma protuberans and a type of bone marrow condition known as aggressive systemic mastocytosis.
The tablet must be taken orally and swallowed whole with water and should not be crushed, chewed, or opened. The prescribed dose and duration of the Imatinib 400mg Tablet depend on the patient's condition and response to treatment. It is taken with food to reduce stomach-related problems. Patients are advised not to change the dosage and timings prescribed by the doctors because it can cause severe side effects.
Common side effects include nausea, vomiting, diarrhea, abdominal discomfort, muscle cramps, fatigue, headache, skin rash, and swelling around the eyes, face, hands, or ankles. A few patients can undergo severe side effects, including severe fluid retention, liver problems, significant bleeding, severe skin reactions and heart problems. Most of the Imatinib 400mg Tablet side effects can leave when the body adapts to the medicine. However, report to your doctor if you experience serious side effects.
The medicine may harm an unborn baby. Women who can become pregnant should use effective contraception during treatment. Patients must list all medicines, supplements, and herbal products that they are taking. The Imatinib 400mg Tablet must be used under medical oversight or medical supervision only. Attend regular tests and follow-ups to monitor the medicine response and reduce side effects. Before making any adjustments, changing the dose, or stopping the treatment, consult with your doctor to maximize the benefit.
Quick Product Facts
| Field | Publication wording |
|---|---|
| Brand | glivec |
| Generic / Active Ingredient | Imatinib |
| Strength | 400 |
| Dosage Form | Tablet |
| Manufacturer / Marketer | novartis |
| Pack Size | 30 |
| Prescription Required | Yes |
| Therapeutic Categories | Cancer Medicines |
| Uses | Blood Cancer |
Uses and Indications
Blood Cancer
Side Effects of Glivec 400mg Tablet
The human body reacts differently to Glivec 400mg Tablet(Imatinib 400mg). Response or undesired symptoms vary from individual to individual. Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention.
Some of the common side effects of Glivec 400mg:
● Muscle cramp
● Musculoskeletal (bone, muscle or joint) pain
● Rash
● Weight gain
● Edema (swelling)
● Nausea
● Vomiting
● Diarrhea
● Fatigue
● Abdominal pain
● Bleeding
● Breathing problems
● Cough
● Dizziness
● Dry eye
● Hemorrhage
However, if the symptoms don't disappear with time or you have severe side effects, then consult your doctor immediately.
Glivec 400mg Tablet Dosage and How To Take It
Take Glivec 400mg Tablet(Imatinib 400mg) in dosage as prescribed by the doctor. Dosage and the duration determined as per stage & type of cancer and the patients health condition. This tablet should be swallowed as a whole with water. Don't crush, chew, or break the tablet. It should be taken with food. Never skip a dose or double dose.
Safety Advice for Glivec 400mg Tablet
- ● Alcohol: Avoid the consumption of alcohol while taking Glivec 400mg Tablet(Imatinib 400mg), as alcohol can decrease the effectiveness of the medicine as well as worsen the symptoms
- ● Pregnancy: Do not take Glivec 400mg Tablet without consulting the doctor in case of pregnancy, as it is an unsafe to take it during this period.
- ● Breastfeeding: Breastfeeding women should discuss the potential risks and benefits of the Glivec 400mg Tablet(Imatinib 400mg) with their healthcare provider before starting treatment.
- ● Driving: Glivec 400mg Tablet may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving.
- ● Kidney: Share your medical history with the doctor before starting the treatment with Glivec 400mg Tablet(Imatinib 400mg). Do not take it without consulting a doctor if you have any kidney related issue.
- ● Liver: Share your medical history with the doctor before starting the treatment with Glivec 400mg Tablet(Imatinib 400mg). Do not take it without consulting a doctor if you have any liver related issue.
FAQs About Glivec 400mg Tablet
What is the use of Glivec 400mg Tablet?
Glivec 400mg Tablet(Imatinib 400mg) is used to treat various types of cancer including chronic myeloid leukemia & acute lymphocytic leukemia and gastrointestinal stromal tumors.
What are the adverse impact of Glivec 400mg Tablet on body?
Some common side effects patients may experience, such as weight gain, bleeding, less hunger, vomiting, nausea, headache, etc.
How to take Glivec 400mg Tablet(Imatinib 400mg)?
Take Glivec 400mg Tablet in exact dosage as prescribed by the doctor. Take it with water and don't miss or double the dose.
How does Glivec 400mg Tablet works?
Glivec 400mg is an anticancer medicine that works by blocking the specific enzyme to inhibit the growth & multiplication of cancer cells.
Is it safe to take Glivec 400mg Tablet in liver related condition?
No, don't take Glivec 400mg Tablet(Imatinib 400mg) in case of liver related condition without consulting the doctor
References
● Ma, Z., Zhao, J., Li, S., Gao, F., Zhang, C., Wu, L., & Lin, Y. (2024). Imatinib-induced ulcerative colitis. Journal of Oncology Pharmacy Practice, 30(6), 1111-1117.
● Nikolova, Z., Peng, B., Hubert, M., Seiberling, M., Keller, U., Ho, Y. Y., ... & Capdeville, R. (2004). Bioequivalence, safety, and tolerability of imatinib tablets compared with capsules. Cancer chemotherapy and pharmacology, 53(5), 433-438.
● de Lemos, M. L., & Kyritsis, V. (2015). Clinical efficacy of generic imatinib. Journal of Oncology Pharmacy Practice, 21(1), 76-79.
● Peng, B., Lloyd, P., & Schran, H. (2005). Clinical pharmacokinetics of imatinib. Clinical pharmacokinetics, 44(9), 879-894.
● WAEC, N., & a Doctor, C. Imatib 400mg Tablet 10? S.
Marketer Details
Novartis
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