Laronib 100mg Capsule (Larotrectinib)
Laronib 100mg Capsule (Larotrectinib)

Laronib 100mg Capsule (Larotrectinib)

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Manufactured By

Everest

Pack Of

30

Salt Composition

Larotrectinib

Storage

At a Cool Place

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ALL SUBSTITUTES

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Overview

Laronib 100mg Capsule is an anticancer medicine. It is prescribed to the patients with solid tumors that have a neurotrophic tyrosine receptor kinase (NTRK) gene fusion. It contains Larotrectinib as an active ingredient that works by inhibit the action of specific enzyme to control the disease spread. It should be taken under strict medical supervision.

Indication

Certain types of cancer, Stomach Cancer


Side Effects

Side effects are undesirable symptoms that can result from any medical treatment. Like any other medicine, Laronib 100mg Capsule(Larotrectinib 100mg) also causes some adverse impact on the body, most of which resolve without any medical attention.
Some common side effects include:
● Anemia
● Fatigue
● Hypoalbuminemia
● Increased alkaline phosphatase
● Nausea
● Dizziness
● Vomiting
● Cough
● Constipation
● Neutropenia
● Diarrhea
● Pyrexia
● Peripheral edema
● Increased weight
● Headache
● Muscular weakness
● Decreased appetite
● Abdominal pain or Back pain
However, if the symptoms don't disappear with time or you have severe side effects, then consult your doctor immediately.

How To Use

Take Laronib 100mg Capsule(Larotrectinib Capsule) in exact dose as prescribed by the doctor. The typical dose of this capsule varies with age and overall health factor of the patient. It can be taken with or without food but at a fixed time each day to get better results. It should be swallowed as a whole with water without crushing, chewing, or opening the capsule. Don't miss a dose or overdose the medicine.

Reference

● Drilon, A. E., DuBois, S. G., Farago, A. F., Geoerger, B., Grilley-Olson, J. E., Hong, D. S., ... & Doz, F. P. (2019). Activity of larotrectinib in TRK fusion cancer patients with brain metastases or primary central nervous system tumors.
● Hong, D. S., DuBois, S. G., Kummar, S., Farago, A. F., Albert, C. M., Rohrberg, K. S., ... & Drilon, A. (2020). Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials. The Lancet Oncology, 21(4), 531-540.
● Carlson, J. J., Italiano, A., Brose, M. S., Federman, N., Lassen, U., Kummar, S., & Sullivan, S. D. (2022). Comparative effectiveness of larotrectinib and entrectinib for TRK fusion cancer. The American journal of managed care, 28(2 Suppl), S26.
● Scott, L. J. (2019). Larotrectinib: first global approval. Drugs, 79(2), 201-206.
● Drilon, A., Laetsch, T. W., Kummar, S., DuBois, S. G., Lassen, U. N., Demetri, G. D., ... & Hyman, D. M. (2018). Efficacy of larotrectinib in TRK fusion–positive cancers in adults and children. New England Journal of Medicine, 378(8), 731-739.

Safety Advice

  • ● Alcohol: Avoid the consumption of alcohol while Laronib 100mg Capsule(Larotrectinib 100mg), as alcohol can decrease the effectiveness of the medicine as well as worsen the symptoms
  • ● Pregnancy: Do not take Laronib 100mg Capsule without consulting the doctor in case of pregnancy, as it is an unsafe to take it during this period.
  • ● Breastfeeding: Breastfeeding women should discuss the potential risks and benefits of the Laronib 100mg Capsule(Larotrectinib 100mg) with their healthcare provider before starting treatment.
  • ● Driving: Laronib 100mg Capsule may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving.
  • ● Kidney: Laronib 100mg Capsule(Larotrectinib 100mg) is safe for use in kidney disease if prescribed by the doctor. No dosage adjustment is necessary for this Tablet.
  • ● Liver: Share your medical history with the doctor before starting the treatment with Laronib 100mg Capsule(Larotrectinib 100mg). Do not take it without consulting a doctor if you have any liver related issue.

FAQs

Is it safe to take the Laronib 100mg Capsule(Larotrectinib) during pregnancy or breastfeeding?

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Consumption of Laronib during pregnancy or breastfeeding is considered to be unsafe, especially without doctor's advice.

Can I drive after taking Laronib 100mg Capsule(Larotrectinib)?

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It is unsafe to drive after taking treatment with this medicine as lack of concentration or dizziness is the common side effect of Laronib 100mg Capsule.

Is it safe to take other medicine with Laronib 100mg Capsule?

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As Laronib 100mg Capsule can interact with some medicine. It is advisable to inform your doctor about any medicine you are taking.

What types of diseases are treatable with Laronib 100mg Capsule?

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Laronib 100mg Capsule(Larotrectinib) prescribed to the patients with solid tumors with specific mutations.

What are the common side effects of Laronib 100mg Capsule?

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There are some common yet manageable side effects of taking Laronib 100mg Capsule that include diarrhea, rash, dry skin, nausea, vomiting, loss of appetite, etc.

Marketer Details

Everest

Rating and Reviews

4.4/5

9 Reviews

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Author Details

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Written By:

Nonish Sharma

I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More


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Reviewed By:

Vaibhav Shakya

Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More

Last Updated: 04 Aug 2026 | 00:23 am (IST)

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