Orgovyx 120mg Tablet (Relugolix)

Orgovyx 120mg Tablet is a prescription-based anticancer medicine used in the treatment of advanced prostate cancer. The active ingredient of the Orgovyx is Relugolix, which belongs to the drug class of gonadotropin-releasing hormone (GnRH) receptor antagonists. Orgovyx is an androgen deprivation therapy (ADT) medication that reduces testosterone levels, which are required by the prostate cancer cells for growth. Relugolix 120mg Tablet is used as monotherapy and given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.

The tablet is taken orally and exactly as prescribed by the doctor. The tablet must be swallowed as whole with water and should not be crushed, chewed, or broken. It is usually taken with or without food. Relugolix 120mg Tablet is started with a loading dose of 360mg on the first day, followed by 120mg once daily from the second day onwards. A doctor decides the dose and timings according to the patient's condition, combination therapy, clinical response, and stage of cancer. Patients are advised not to change the dosage because it can lead to severe side effects.

Common side effects include hot flushes, increased sweating, tiredness, muscle or joint pain, decreased sex drive, erectile dysfunction, and changes in weight. A few patients can undergo severe side effects, including heart rhythm abnormalities, cardiovascular problems, severe liver problems, and metabolic changes. Most of the Relugolix 120mg tablet side effects can leave when the body adapts to the medicine. However, if any side effects persist, inform your doctor immediately.

Women who are pregnant or may become pregnant should avoid this medicine. Breastfeeding is not recommended, and consult with your doctor. Patients must list all medicines, supplements, and herbal products that they are taking. The Relugolix 120mg Tablet must be used under medical oversight or medical supervision only. Attend regular tests and follow-ups to monitor the medicine response and reduce side effects. Before making any adjustments, changing the dose, or stopping the treatment, consult with your doctor to maximize the benefit.

Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer

The human body shows undesired symptoms after taking Relugolix 120mg Tablet (Orgovyx). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.

Orgovyx 120mg Tablet (Relugolix) is a prescription-based anticancer drug that should be administered orally. It is advised to take this capsule after consulting your healthcare expert.

This tablet should be swallowed as a whole with water. Don't crush, chew, or break it. It can be taken with or without food. Never skip a dose or double dose.

● Osuga, Y., Enya, K., Kudou, K., & Hoshiai, H. (2019). Relugolix, a novel oral gonadotropin-releasing hormone antagonist, in the treatment of pain symptoms associated with uterine fibroids: a randomized, placebo-controlled, phase 3 study in Japanese women. Fertility and sterility, 112(5), 922-929.
● Tutrone, R., Saad, F., George, D. J., Tombal, B., Bailen, J. L., Cookson, M. S., ... & Shore, N. D. (2024). Testosterone recovery for relugolix versus leuprolide in men with advanced prostate cancer: results from the phase 3 HERO study. European urology oncology, 7(4), 906-913.
● Markham, A. (2019). Relugolix: first global approval. Drugs, 79(6), 675-679.
● Shirley, M. (2023). Relugolix: a review in advanced prostate cancer. Targeted Oncology, 18(2), 295-302.
● Shore, N. D., Saad, F., Cookson, M. S., George, D. J., Saltzstein, D. R., Tutrone, R., ... & Tombal, B. (2020). Oral relugolix for androgen-deprivation therapy in advanced prostate cancer. New England Journal of Medicine, 382(23), 2187-2196.