Palboxen 125mg Capsule (Palbociclib)
Prescription RequiredManufactured By
Everest
Pack Of
21
Salt Composition
Palbociclib
Storage
Keep in cold place
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Overview
Palboxen 125mg Capsule is a prescription-based anticancer medicine used in the treatment of hormone receptor-positive or human epidermal growth factor 2 negative breast cancer that is locally advanced or spread to other parts of the body.
The active ingredient of the Palboxen is Palbociclib which belongs to the drug class of cyclin-dependent kinase inhibitors. This drug functions to inhibit the enzyme cyclin dependent kinase 4 and 6 thereby stopping the growth of cancer cells.
It further acts on the positive estrogen hormone receptor breast cancer cells by blocking their cell cycle growth. Palbociclib is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
Indication
Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer
Side Effects
The human body shows undesired symptoms after taking Palbociclib 125mg Capsule (Palboxen). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Common Side Effects
- Some of the common side effects of Palbociclib Capsule are mentioned below:
- ● Fever
- ● Diarrhea
- ● Fatigue
- ● Hair loss
- ● Rash
- ● Vomiting
- ● Nausea
- ● Decreased appetite
- ● Infection
- ● Stomatitis (Inflammation of the mouth)
- ● Anemia (low number of red blood cells)
- ● Weakness
- ● Decreased white blood cell count
- ● Decreased blood cells (red cells, white cells, and platelets)
How To Use
Take Palboxen 125mg Capsule (Palbociclib) in dosage as prescribed by the doctor. Dosage and the duration determined as per stage & type of cancer and the patients health condition.
This capsule should be swallowed as a whole with water. Don't crush, chew, or break the capsule. It should be taken with food. Never skip a dose or double dose.
Reference
● Serra, F., Lapidari, P., Quaquarini, E., Tagliaferri, B., Sottotetti, F., & Palumbo, R. (2019). Palbociclib in metastatic breast cancer: current evidence and real-life data. Drugs in context, 8, 212579.
● Finn, R. S., Martin, M., Rugo, H. S., Jones, S., Im, S. A., Gelmon, K., ... & Slamon, D. J. (2016). Palbociclib and letrozole in advanced breast cancer. New England journal of medicine, 375(20), 1925-1936.
● Beaver, J. A., Amiri-Kordestani, L., Charlab, R., Chen, W., Palmby, T., Tilley, A., ... & Cortazar, P. (2015). FDA approval: palbociclib for the treatment of postmenopausal patients with estrogen receptor–positive, HER2-negative metastatic breast cancer. Clinical cancer research, 21(21), 4760-4766.
● Turner, N. C., Ro, J., André, F., Loi, S., Verma, S., Iwata, H., ... & Cristofanilli, M. (2015). Palbociclib in hormone-receptor–positive advanced breast cancer. New England Journal of Medicine, 373(3), 209-219.
● Dhillon, S. (2015). Palbociclib: first global approval. Drugs, 75(5), 543-551.
Safety Advice
- • Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Palbociclib 125mg Capsule (Palboxen). It is advised to consult your doctor for further information.
- • Pregnancy: Palboxen 125mg Capsule (Palbociclib) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- • Breastfeeding: Palbociclib 125mg Capsule (Palboxen) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- • Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Palboxen 125mg Capsule (Palbociclib).
- • Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Palbociclib 125mg Capsule (Palboxen).
- • Liver: Inform your doctor before starting Palboxen 125mg Capsule (Palbociclib) if you have liver disease to avoid any serious side effects
FAQs
Why do doctors prescribe Palboxen 125mg Capsule (Palbociclib)?
This medicine is given to adults diagnosed with hormone receptor-positive or human epidermal growth factor 2 negative breast cancer.
What is the right way of taking the Palbociclib Capsule?
Palbociclib Capsule is taken orally with or without food as per the doctor's advice. It is consumed at the same time each day for better results. It is recommended not to crush, chew, or split the capsules; take them as a whole.
What should be done if you feel nauseous after taking Palboxen?
Nausea and vomiting are some of the side effects seen after taking Palboxen 125mg Capsules. It is advised to consult if you're observing it continually and severely.
Is it safe to take another dose of Palboxen Capsule if lose previous dose during vomiting?
No, do not take another dose if you lost it during vomiting. It is advised just to calm down and rest properly. Don't compensate for missed doses with another day's dose.
Does Palbociclib 125mg Capsule (Palboxen) cause a drop in blood cell counts?
Yes, taking Palbociclib 125mg Capsule may cause decrease in level of the blood cells and severely result in anemia. Your doctor must examine the blood count at regular interval.
What is the drug class of Palboxen 125mg Capsule?
Palboxen belongs to the drug class of target therapy anticancer medicine that belongs to cyclin dependent kinase drug class. It damages the working of the protein and prevents the growth & proliferation of the cancer cells.
Marketer Details
Everest
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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