Palbolieva 125mg Capsule (Palbociclib)
Prescription RequiredManufactured By
Allieva
Pack Of
21
Salt Composition
Palbociclib
Storage
Keep in cold place
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Overview
Palbolieva 125mg Capsule is an oral targeted therapy based anticancer medicine with active ingredient Palbociclib. This capsule is used to treat patients with certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) in advanced stages. It acts by blocking the CDK 4 and 6 and also targeting estrogen to slow down multiplication and progression of cancer cells. It should be taken exactly as prescribed by the doctor.
Indication
Breast Cancer, Metastatic Cancer
Side Effects
Like any other anticancer medicine, Palbolieva 125mg Capsule(Palbociclib 125mg) also shows some side effects, which vary from one person to another according to various health factors. Most of them are mild, and some are serious enough to need immediate medical attention.
Some Common side effects include:
● Tiredness
● Hair loss
● Dry skin, rash
● Infections
● Low blood cell counts
● Decreased of appetite
● Nausea, vomiting
● Diarrhea
● Swelling of lips and mouth
● Changes in taste
● Nose bleed
● Dry eye, blurred vision, increased tearing
Contact the doctor immediately in case of any unusual or persistent side effects.
Common Side Effects
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How To Use
The recommended dose of Palbolieva 125mg Capsule(Palbociclib 125mg) is once daily for 21 consecutive days followed by 7 days off (28-day cycle). However, the doctor determines the dosage and duration as per stage & type of cancer and the patients health condition. This tablet should be swallowed as a whole with water. Don't crush, chew, or break the capsule. It should be taken with food. Never skip a dose or double dose.
Reference
● Wedam, S., Fashoyin-Aje, L., Bloomquist, E., Tang, S., Sridhara, R., Goldberg, K. B., ... & Beaver, J. A. (2020). FDA approval summary: palbociclib for male patients with metastatic breast cancer. Clinical Cancer Research, 26(6), 1208-1212.
● Turner, N. C., Ro, J., André, F., Loi, S., Verma, S., Iwata, H., ... & Cristofanilli, M. (2015). Palbociclib in hormone-receptor–positive advanced breast cancer. New England Journal of Medicine, 373(3), 209-219.
● Cadoo, K. A., Gucalp, A., & Traina, T. A. (2014). Palbociclib: an evidence-based review of its potential in the treatment of breast cancer. Breast Cancer: Targets and Therapy, 123-133.
● Finn, R. S., Martin, M., Rugo, H. S., Jones, S., Im, S. A., Gelmon, K., ... & Slamon, D. J. (2016). Palbociclib and letrozole in advanced breast cancer. New England journal of medicine, 375(20), 1925-1936.
● Dhillon, S. (2015). Palbociclib: first global approval. Drugs, 75(5), 543-551.
Safety Advice
- ● Alcohol: Avoid the consumption of alcohol while taking Palbolieva 125mg Capsule(Palbociclib 125mg), as alcohol can reduce the effectiveness of the medicine and worsen the symptoms.
- ● Pregnancy: Palbolieva 125mg Capsule is not recommended during pregnancy as it is unsafe for the developing fetus.
- ● Breastfeeding: Breastfeeding women should discuss the potential risks and benefits of the Palbociclib 125mg Capsule(Palbolieva 125mg Capsule) with their healthcare provider before starting treatment.
- ● Driving: Patients should avoid driving or operating machinery while taking Palbolieva 125mg Capsule if they experience side effects such as fatigue, dizziness, or blurred vision.
- ● Kidney: Avoid Palbociclib 125mg(Palbolieva 125mg Capsule) consumption if you have any liver-related issues because this medicine causes liver toxicity, which can make your condition worse.
- ● Liver: Avoid Palbolieva 125mg Capsule consumption if you have any liver-related issues because this medicine causes liver toxicity, which can make your condition worse.
FAQs
Which type of cancer can be treated with Palbolieva 125mg Capsule?
Palbolieva 125mg Capsule(Palbociclib 125mg) is prescribed to treat patients with certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) in advanced stages.
Can I take Palbolieva 125mg Capsule if I have any kidney or liver related problem?
Consumption of Palbolieva 125mg Capsule(Palbociclib 125mg) should be avoided without informing the doctor if you have any kidney or liver-related issues.
How should I take Palbolieva 125mg Capsule(Palbociclib 125mg)?
Palbolieva 125mg should be taken with food. Never skip a dose or double dose.
Are there any possible side effects of taking Palbolieva 125mg?
Unlike any other anticancer medicine Palbolieva 125mg also shows some side effects which include nausea, tiredness, hair loss, dry skin, rash, infections, low blood cell counts, etc.
What should I do if I overdose Palbolieva 125mg Capsule(Palbociclib 125mg)?
In case of an overdose of this capsule, contact your doctor or any healthcare provider and seek medical attention immediately
Marketer Details
Allieva
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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