Nexavar 200mg Tablet (Sorafenib)
Prescription RequiredManufactured By
Bayer pharma
Pack Of
60
Salt Composition
Sorafenib
Storage
Keep in cold place
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Overview
Nexavar 200mg Tablet is a prescription-based anticancer medicine used in the treatment of multiple cancers such as liver cancer, kidney cancer, and thyroid cancer. The active ingredient of the Nexavar is sorafenib, which belongs to the drug class of tyrosine kinase inhibitors. It works by blocking specific proteins that help the cancer cell in growth and the development of new blood vessels that supply tumors. This action can stop cancer progression and cancer load in the body.
The tablet is taken orally and exactly as prescribed by the doctor. The tablet must be swallowed as whole with water and should not be crushed, chewed, or broken. It is usually taken on an empty stomach or with a low-fat meal, as it might affect how the medicine is absorbed. Sorafenib 200mg Tablet is given once daily, and a doctor decides the dose and timings according to the patient's condition, combination therapy, clinical response, and stage of cancer. Patients are advised not to change the dosage because it can lead to severe side effects.
Common side effects include diarrhea, nausea, vomiting, tiredness, weakness, loss of appetite, weight loss, skin rash, hair loss, and hand-foot skin reaction. A few patients can undergo severe side effects, including severe bleeding, heart problems, severe high blood pressure, liver damage, blood clots and gastrointestinal perforation. Most of the Sorafenib 200mg Tablet side effects can leave when the body adapts to the medicine. However, report to your doctor if you experience serious side effects.
The medicine may harm an unborn baby and should not be used during pregnancy. Inform your doctor before undergoing surgery or dental procedures because the drug may affect wound healing. Patients must list all medicines, supplements, and herbal products that they are taking. The Sorafenib 200mg Tablet must be used under medical oversight or medical supervision only. Attend regular tests and follow-ups to monitor the medicine response and reduce side effects. Before making any adjustments, changing the dose, or stopping the treatment, consult with your doctor to maximize the benefit.
Indication
liver cancer
Side Effects
The human body shows undesired symptoms after taking Sorafenib 200mg Tablet (Nexavar). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Some of the common side effects of Nexavar Tablet are mentioned below:
● Nausea, stomach pain, diarrhea
● Tiredness and weakness
● Infection
● Hair thinning and patchy hair loss
● Rash
● Weight loss
● Loss of appetite
● Low levels of calcium in the blood
● Flu-like illness
Serious Side Effects
- ● Decreased blood flow to the heart
- ● Increased risk of bleeding (blood in urine, stool, vomit, cough, etc)
- ● High BP
- ● Skin problems
- ● Liver problems
- ● Problems in wound healing
How To Use
Sorafenib 200mg Tablet (Nexavar) is a prescription-based anticancer drug that should be administered orally. It is advised to take this tablet after consulting your healthcare expert. Take this tablet on an empty stomach for better results.
Before starting this medicine, please inform your doctor about your medical history. If you experience any signs and symptoms while taking this medication that are not manageable, do not ignore those symptoms because they may lead to a higher risk.
Reference
● Thomas, L., Lai, S. Y., Dong, W., Feng, L., Dadu, R., Regone, R. M., & Cabanillas, M. E. (2014). Sorafenib in metastatic thyroid cancer: a systematic review. The oncologist, 19(3), 251-258.
● Porta, C., Paglino, C., Imarisio, I., & Ferraris, E. (2009). Sorafenib tosylate in advanced kidney cancer: past, present and future. Anti-cancer drugs, 20(6), 409-415.
● Li, Y., Gao, Z. H., & Qu, X. J. (2015). The adverse effects of sorafenib in patients with advanced cancers. Basic & clinical pharmacology & toxicology, 116(3), 216-221.
● Rini, B. I. (2006). Sorafenib. Expert opinion on pharmacotherapy, 7(4), 453-461.
● Wilhelm, S., Carter, C., Lynch, M., Lowinger, T., Dumas, J., Smith, R. A., ... & Kelley, S. (2006). Discovery and development of sorafenib: a multikinase inhibitor for treating cancer. Nature reviews Drug discovery, 5(10), 835-844.
Safety Advice
- • Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Sorafenib 200mg Tablet (Nexavar). It is advised to consult your doctor for further information.
- • Pregnancy: Nexavar 200mg Tablet (Sorafenib) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- • Breastfeeding: Sorafenib 200mg Tablet (Nexavaris probably not safe if you're breastfeeding. Kindly consult your doctor.
- • Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Nexavar 200mg Tablet (Sorafenib).
- • Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Nexavar 200mg Tablet (Sorafenib).
- • Liver: Inform your doctor before starting Sorafenib 200mg Tablet (Nexavar) if you have liver disease to avoid any serious side effects
FAQs
Is it safe for diabetic patients to take Nexavar 200mg Tablet (Sorafenib)?
There are chances that this tablet may affect blood glucose levels. This decision is taken by the doctor after assessing blood glucose levels after taking the medicine. It varies from person to person.
What are the important things to keep in mind while taking Nexavar Tablet?
It is advised to strictly cut off high-fat foods while undergoing treatment with this medicine. It is important to tell your doctor if you're already taking any prescribed medicines or supplements.
Is it possible to take Sorafenib 200mg Tablet (Nexavar) along with other treatments to increase the efficiency?
Nexavar 200mg Tablet is used as a monotherapy drug. It means this medicine is used alone and not in combination with other treatments like radiotherapy or chemotherapy for better results.
Does taking Sorafenib 200mg Tablet (Nexavar) cause any changes in the blood sugar levels?
Yes, some chances of taking Sorafenib Tablet can lead to fluctuations in blood sugar levels. They can decrease the blood glucose level to a limit where the person may feel unconscious. It is crucial to get blood sugar levels checked regularly. Moreover, consult your doctor if the dose of anti-diabetic medicines needs to be adjusted.
What are the possible signs observed to check if the patient is responding to Nexavar 200mg Tablet (Sorafenib)?
The healthcare expert advises to get your regular scans done in order to check the size of tumor. It is also important to get your blood test, KFT & LFT done to check the affect of the medicine on vitals.
Marketer Details
Bayer pharma
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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