Imfinzi 120mg Injection (Durvalumab)
Prescription RequiredManufactured By
Astra zeneca
Pack Of
1
Salt Composition
Durvalumab
Storage
Keep in cold place
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ALL SUBSTITUTES
Imfinzi 500mg Injection
Overview
Imfinzi 120mg Injection is a prescription-based anticancer medicine used in the treatment of non-small cell lung cancer that has not spread outside your chest, small cell lung cancer, and biliary tract cancers.
The active ingredient of the Imfinzi is Durvalumab which belongs to the drug class of PD-1 monoclonal antibodies. This injection works through inhibiting a protein, known as PD-L1, produced by cancer cells to shield themselves from an immune response.
The drug works on blocking PD-L1 and enabling T-cells to recognize and attack cancer cells. Durvalumab Injection is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
Indication
Lung Cancer, Endometrial cancer, Liver Cancer, Duct Cancer, Gallbladder Cancer
Side Effects
The human body shows undesired symptoms after taking Imfinzi 120mg Injection (Durvalumab). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Common Side Effects
- Some of the common side effects of Imfinzi Injection are mentioned below:
- ● Rash
- ● Fever
- ● Chills
- ● Cough
- ● Tiredness
- ● Weight loss
- ● Muscles pain
- ● Fast heart rate
- ● Painful urination
- ● Flu-like symptoms
- ● swelling of the legs
- ● Fungal infection in the mouth
Serious Side Effects
- ● Abnormal night sweating
- ● Inflammation in throat and nose
- ● Upper respiratory tract infection
- ● Increased blood creatinine level
How To Use
Imfinzi 120mg Injection (Durvalumab) is a prescription-based anticancer drug. It is advised to take this injection after consulting your healthcare expert. This medicine should be given intravenously by an experienced nurse or doctor. Please do not self-administer.
Reference
● Alvarez-Argote, J., & Dasanu, C. A. (2019). Durvalumab in cancer medicine: a comprehensive review. Expert Opinion on Biological Therapy, 19(9), 927-935.
● Antonia, S. J., Balmanoukian, A., Brahmer, J., Ou, S. H. I., Hellmann, M. D., Kim, S. W., ... & Segal, N. H. (2019). Clinical activity, tolerability, and long-term follow-up of durvalumab in patients with advanced NSCLC. Journal of thoracic Oncology, 14(10), 1794-1806.
● Al-Salama, Z. T. (2021). Durvalumab: a review in extensive-stage SCLC. Targeted Oncology, 16(6), 857-864.
● Powles, T., O'Donnell, P. H., Massard, C., Arkenau, H. T., Friedlander, T. W., Hoimes, C. J., ... & Hahn, N. M. (2017). Efficacy and safety of durvalumab in locally advanced or metastatic urothelial carcinoma: updated results from a phase 1/2 open-label study. JAMA oncology, 3(9), e172411.
● Faivre-Finn, C., Vicente, D., Kurata, T., Planchard, D., Paz-Ares, L., Vansteenkiste, J. F., ... & Antonia, S. J. (2021). Four-year survival with durvalumab after chemoradiotherapy in stage III NSCLC—an update from the PACIFIC trial. Journal of Thoracic Oncology, 16(5), 860-867.
Safety Advice
- ● Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Imfinzi 120mg Injection (Durvalumab). It is advised to consult your doctor for further information.
- ● Pregnancy: Imfinzi 120mg Injection (Durvalumab) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- ● Breastfeeding: Imfinzi 120mg Injection (Durvalumab) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- ● Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Imfinzi 120mg Injection (Durvalumab).
- ● Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Imfinzi 120mg Injection (Durvalumab).
- ● Liver: Inform your doctor before starting Imfinzi 120mg Injection (Durvalumab) if you have liver disease to avoid any serious side effects.
FAQs
What type of cancer is treated using Imfinzi 120mg Injection (Durvalumab)?
Imfinzi 120mg Injection is an prescription based anticancer medicine used to treat advanced stage non-small cell lung cancer (NSCLC), biliary tract cancer, liver cancer, and endometrial cancer.
Who are not allowed to take Imfinzi 120mg Injection (Durvalumab)?
This drug is not considered safe in patients who have autoimmune diseases, such as rheumatoid arthritis, or multiple sclerosis. They can get severe side effects after taking Imfinzi 120mg injection.
Can Imfinzi 120mg Injection works as combination drug?
Yes, Imfinzi 120mg Injection is used as combination drug to boost the immunity to stop the growth of cancer cells.
How will Imfinzi 120mg Injection (Durvalumab) given to cancer patients?
Imfinzi 120mg Injection should be given intravenously by an experienced nurse or doctor. Please do not self-administer.
What precautions should I take during treatment of Imfinzi 120mg Injection (Durvalumab)?
Avoid exposure to sun and infections, report if observe any unusual symptoms, and share your medical history with your healthcare expert, especially if you have autoimmune conditions, pregnant, planning to be pregnant, or breastfeeding.
Marketer Details
Astra zeneca
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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