Afatin 40mg Tablet (Afatinib)
Prescription RequiredManufactured By
Bdr pharma
Pack Of
28
Salt Composition
Afatinib
Storage
Keep in cold place
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Overview
Afatin 40mg Tablet is a targeted therapy-based anticancer medicine. It contains afatinib dimaleate as an active ingredient that belongs to the tyrosine kinase inhibitor class of drugs. The doctor prescribes Afatin 40mg to treat non-small cell lung cancer with certain mutations of EGFR in adults.
It works by binding with specific receptors such as EGFR, HER2, and HER4 to slow down the progression of cancer and control the growth of cancer cells. Take it as prescribed by the doctor at the fixed time each day to get better results.
Indication
Lung Cancer, monotherapy
Side Effects
Afatin 40mg Tablet(Afatinib 40mg) is a strong anticancer medicine that may show certain adverse while manageable impact on the body during the treatment. As these effects resolve on their own without any special medical attention. However, if you ever experience serious or unusual side effects contact your healthcare professional immediately.
Some common side effects include:
● Diarrhea
● Rash
● Dry skin
● Nausea
● Vomiting
● Loss of appetite
● Itching
● Stomatitis (Inflammation of the mouth)
● Nail disorder
How To Use
Take the Afatin 40mg Tablet (Afatinib 40mg) in the dosage as prescribed by the doctor. Dosage and the duration were determined as per the stage of cancer & the patient's health condition. This tablet should be swallowed as a whole with water. Don't crush, chew, or break the tablet. It should be taken on an empty stomach. Never skip a dose or double dose.
Reference
● Park, K., Tan, E. H., O'Byrne, K., Zhang, L., Boyer, M., Mok, T., ... & Paz-Ares, L. (2016). Afatinib versus gefitinib as first-line treatment of patients with EGFR mutation-positive non-small-cell lung cancer (LUX-Lung 7): a phase 2B, open-label, randomised controlled trial. The Lancet Oncology, 17(5), 577-589.
● Harvey, R. D., Adams, V. R., Beardslee, T., & Medina, P. (2020). Afatinib for the treatment of EGFR mutation-positive NSCLC: A review of clinical findings. Journal of Oncology Pharmacy Practice, 26(6), 1461-1474.
● Schuler, M., Yang, J. H., Park, K., Kim, J. H., Bennouna, J., Chen, Y. M., ... & Popovych, O. (2016). Afatinib beyond progression in patients with non-small-cell lung cancer following chemotherapy, erlotinib/gefitinib and afatinib: phase III randomized LUX-Lung 5 trial. Annals of Oncology, 27(3), 417-423.
● Keating, G. M. (2014). Afatinib: a review of its use in the treatment of advanced non-small cell lung cancer. Drugs, 74(2), 207-221.
● Dungo, R. T., & Keating, G. M. (2013). Afatinib: first global approval. Drugs, 73(13), 1503-1515.
● Wind, S., Schnell, D., Ebner, T., Freiwald, M., & Stopfer, P. (2017). Clinical pharmacokinetics and pharmacodynamics of afatinib. Clinical pharmacokinetics, 56(3), 235-250.
Safety Advice
- ● Alcohol: Consumption of alcohol during the treatment with Afatin 40mg Tablet(Afatinib 40mg) is usually doesn't show any major issues.
- ● Pregnancy: Do not take Afatin 40mg Tablet without consulting the doctor in case of pregnancy, as it is an unsafe to take it during this period.
- ● Breastfeeding: Breastfeeding women should discuss the potential risks and benefits of the Afatin 40mg Tablet(Afatinib 40mg) with their healthcare provider before starting treatment.
- ● Driving: Afatin 40mg Tablet may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving.
- ● Kidney: Afatin 40mg Tablet (Afatinib 40mg) is safe for use in kidney disease if prescribed by the doctor. No dosage adjustment is necessary for this tablet.
- ● Liver: Afatin 40mg Tablet is safe for use in liver disease if prescribed by the doctor. No dosage adjustment is necessary for this tablet.
FAQs
What is the use of Afatin 40mg Tablet(Afatinib 40mg)?
Afatin 40mg Tablet is used to treat non-small cell lung cancer with certain mutations of EGFR in adults.
What are the adverse impact of Afatin 40mg Tablet(Afatinib 40mg) on body?
Some common side effects patients may experience, such as edema (swelling), anemia (low number of red blood cells), rash, abdominal pain, constipation, decreased appetite, dizziness, hot flashes, etc.
How to take Afatin 40mg Tablet?
Take the Afatin 40mg Tablet (Afatinib 40mg) in the exact dosage as prescribed by the doctor. Don't miss or double the dose.
How does Afatin 40mg Tablet work?
Afatin 40mg Tablet (Afatinib 40mg) is an anticancer medicine that works by binding with specific receptors such as EGFR, HER2, and HER4 to slow down the progression of cancer and control the growth of cancer cells.
Is Afatin Tablet an immunotherapy or chemotherapy medicine?
Afatin 40mg Tablet is neither an immunotherapy nor a chemotherapy. It belongs to the kinase inhibitor class of anti-cancer drugs. It works by blocking a group of proteins that are involved in the growth and spread of cancer cells.
Marketer Details
Bdr pharma
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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