Afanat 40mg Tablet (Afatinib)
Prescription RequiredManufactured By
Natco
Pack Of
28
Salt Composition
Afatinib
Storage
Keep in cold place
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Overview
Afanat 40mg Tablet is an anticancer medicine that contains Afatinib as an active ingredient. It is used in the treatment of non-small cell lung cancer in adult patients who have certain mutations of epidermal growth factor receptor (EGFR).
It is a second-generation tyrosine kinase inhibitor that works by inhibiting the enzyme receptors (EGFR, HER2, and HER4) that are responsible for the growth of cancer cells. Hence, resulting in the down regulation of signaling pathways that stop or slow the spread of cancer. It should be taken in dose and duration as advice by the doctor. Don't take more than the recommended dose.
Indication
Lung Cancer
Side Effects
Afanat 40mg Tablet(Afatinib 40mg) is a strong anticancer medicine that may show certain adverse while manageable impact on the body during the treatment. As these effects resolve on their own without any special medical attention. However, if you ever experience serious or unusual side effects contact your healthcare professional immediately.
Some common side effects include:
● Diarrhea
● Rash
● Dry skin
● Nausea
● Vomiting
● Loss of appetite
● Itching
● Stomatitis (Inflammation of the mouth)
● Nail disorder
How To Use
Take Afanat 40mg Tablet(Afatinib 40mg) in dosage as prescribed by the doctor. Dosage and the duration determined as per the patients health condition. This tablet should be swallowed as a whole with water. Don't crush, chew, or break the tablet. It should be taken on an empty stomach. Never skip a dose or double dose.
Reference
● Helena, A. Y., & Pao, W. (2013). Targeted therapies: Afatinib—new therapy option for EGFR-mutant lung cancer. Nature reviews Clinical oncology, 10(10), 551.
● Giordano, P., Manzo, A., Montanino, A., Costanzo, R., Sandomenico, C., Piccirillo, M. C., ... & Morabito, A. (2016). Afatinib: An overview of its clinical development in non-small-cell lung cancer and other tumors. Critical reviews in oncology/hematology, 97, 143-151.
● Soria, J. C., Felip, E., Cobo, M., Lu, S., Syrigos, K., Lee, K. H., ... & Goss, G. D. (2015). Afatinib versus erlotinib as second-line treatment of patients with advanced squamous cell carcinoma of the lung (LUX-Lung 8): an open-label randomised controlled phase 3 trial. The lancet oncology, 16(8), 897-907.
● Kim, Y., Lee, S. H., Ahn, J. S., Ahn, M. J., Park, K., & Sun, J. M. (2019). Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib. Cancer research and treatment: official journal of Korean Cancer Association, 51(2), 502-509.
● Yang, J. C. H., Reguart, N., Barinoff, J., Köhler, J., Uttenreuther-Fischer, M., Stammberger, U., ... & Cohen, E. E. (2013). Diarrhea associated with afatinib: an oral ErbB family blocker. Expert Review of Anticancer Therapy, 13(6), 729-736.
Safety Advice
- ● Alcohol: Avoid the consumption of alcohol while taking Afanat 40mg Tablet(Afatinib 40mg), as alcohol can decrease the effectiveness of the medicine as well as worsen the symptoms
- ● Pregnancy: Do not take Afanat 40mg Tablet without consulting the doctor in case of pregnancy, as it can be unsafe to take it during this period.
- ● Breastfeeding: Breastfeeding women should discuss the potential risks and benefits of the Afanat 40mg Tablet(Afatinib 40mg) with their healthcare provider before starting treatment.
- ● Driving: Afanat 40mg Tablet may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving.
- ● Kidney: Afanat 40mg Tablet(Afatinib 40mg) is safe for use in kidney disease if prescribed by the doctor. No dosage adjustment is necessary for this Tablet..
- ● Liver: Afanat 40mg Tablet(Afatinib 40mg) is safe for use in liver disease if prescribed by the doctor. No dosage adjustment is necessary for this Tablet.
FAQs
Can a patient with kidney related issue take Afanat 40mg Tablet(Afatinib 40mg)?
Yes, it is safe to take Afanat 40mg Tablet in kidney related conditions if prescribed by the doctor.
Which is the best time to take Afanat 40mg Tablet(Afatinib 40mg)?
This tablet should be taken on an empty stomach in exact dose as advice by the doctor at a fix time everyday to get a better result.
What are the common side effects of Afanat 40mg Tablet?
Like any other medicine Afanat 40mg Tablet(Afatinib 40mg) also show some side effects such as diarrhea, rash, dry skin, nausea, vomiting, loss of appetite, itching, etc.
What are the uses of Afanat 40mg Tablet?
As per doctor's prescription Afanat 40mg Tablet uses to treat non-small cell lung cancer in adult patients who have certain mutations of epidermal growth factor receptor (EGFR).
Can I drive after taking Afanat 40mg Tablet(Afatinib 40mg)?
It is unsafe to drive after taking treatment with this medicine as lack of concentration or dizziness is the common side effect of Afanat 40mg Tablet.
Marketer Details
Natco
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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