Venclexta 100mg Tablet (Venetoclax)
Prescription RequiredManufactured By
Abbvie
Pack Of
28
Salt Composition
Venetoclax
Storage
Keep in cold place
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ALL SUBSTITUTES
Ventoxen 100mg Tablet
Overview
Venclexta 100mg Tablet is a prescription-based targeted anticancer medicine used in the treatment of blood cancers, including chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and acute myeloid leukemia (AML). The active ingredient of Venclexta is venetoclax, which belongs to the drug class of BCL-2 inhibitors. It works by targeting and blocking the BCL-2 survival protein in abnormal white blood cells, resulting in programmed cell death. The Venetoclax tablet is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
The tablet must be taken orally and swallowed whole with water and should not be crushed, chewed, or opened. The prescribed dose and duration of the Venetoclax 100mg tablet depend on the patient's condition and response to treatment. It is taken with food at the same time every day. Doctors usually start the treatment at a lower dose and gradually increase according to the patient's response. Patients are advised not to change the dosage and timings prescribed by the doctors because it can cause severe side effects.
Common side effects include nausea, diarrhea, vomiting, constipation, tiredness, decreased appetite, headache, and infections. A few patients can undergo severe side effects, including tumor lysis syndrome (TLS). Most of the Venetoclax 100mg tablet side effects can leave when the body adapts to the medicine. However, report to your doctor if you experience serious side effects.
Pregnant or breastfeeding women should consult their doctor before treatment. Venclexta can interact with CYP3A enzymes; therefore, review it before the treatment. Patients must list all medicines, supplements, and herbal products that they are taking. The Venetoclax 100mg tablet must be used under medical oversight or medical supervision only. Attend regular tests and follow-ups to monitor the medicine response and reduce side effects. Before making any adjustments, changing the dose, or stopping the treatment, consult with your doctor to maximize the benefit.
Indication
Blood cancers like chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and acute myeloid leukemia (AML)
Side Effects
The human body shows undesired symptoms after taking Venclexta 100mg Tablet (Venetoclax). Usually, they disappear with time as the body adjusts to the medicine. These side effects do not need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Common Side Effects
- Some of the common side effects of Venetoclax 100mg Tablet are mentioned below:
- ● Decreased white blood cell count (neutrophils)
- ● Low blood platelets
- ● Anemia (low number of red blood cells)
- ● Diarrhea
- ● Nausea
- ● Upper respiratory tract infection
- ● Cough
- ● Musculoskeletal (bone, muscle or joint) pain
- ● Fatigue
- ● Edema (swelling)
Serious Side Effects
- ● Kidney failure
- ● Tumor lysis syndrome (TLS)
How To Use
Take Venetoclax 100mg Tablet (Venclexta) in dosage as prescribed by the doctor. Dosage and the duration determined as per stage & type of cancer and the patients health condition.
This tablet should be swallowed as a whole with water. Don't crush, chew, or break the tablet. It should be taken with food. Never skip a dose or double dose.
Missed Doses
Reference
● Deeks, E. D. (2016). Venetoclax: first global approval. Drugs, 76(9), 979-987.
● Raedler, L. A. (2017). Venclexta (Venetoclax) first BCL-2 inhibitor approved for high-risk relapsed chronic lymphocytic leukemia.
● Hegishte, Y., Joyce, P., Prestidge, C., & Bremmell, K. (2026). Overcoming the oral delivery challenges of venetoclax: advancing a clinically improved Bcl-2 inhibitor. Drug Delivery and Translational Research, 1-21.
● King, A. C., Peterson, T. J., Horvat, T. Z., Rodriguez, M., & Tang, L. A. (2017). Venetoclax: a first-in-class oral BCL-2 inhibitor for the management of lymphoid malignancies. Annals of Pharmacotherapy, 51(5), 410-416.
● Juárez-Salcedo, L. M., Desai, V., & Dalia, S. (2019). Venetoclax: evidence to date and clinical potential. Drugs in context, 8, 212574.
Safety Advice
- • Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Venclexta 100mg Tablet (Venetoclax). It is advised to consult your doctor for further information.
- • Pregnancy: Venetoclax 100mg Tablet (Venclexta) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- • Breastfeeding: Venclexta 100mg Tablet (Venetoclax) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- • Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Venetoclax 100mg Tablet (Venclexta).
- • Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Venetoclax 100mg Tablet (Venclexta).
- • Liver: Inform your doctor before starting Venclexta 100mg Tablet (Venetoclax) if you have liver disease to avoid any serious side effects
FAQs
Why do doctors prescribe Venetoclax 100mg Tablet (Venclexta)?
This medicine is given to adults diagnosed with blood cancers, including chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and acute myeloid leukemia (AML).
What type of drug is Venclexta 100mg Tablet (Venetoclax)?
Venclexta 100mg Tablet is a targeted therapy drug that inhibits the protein to kill the cancer cells.
What is the right way of taking the Venclexta 100mg Tablet (Venetoclax)?
Venclexta Tablet should be swallowed as a whole with water. Don't crush, chew, or break the tablet. It should be taken with food. Never skip a dose or double dose.
Who should avoid taking Venetoclax 100mg Tablet (Venclexta)?
People diagnosed with severe liver and kidney disorders are advised to consult their healthcare professionals before taking this medicine.
Can the Venetoclax 100mg Tablet (Venclexta) be given in combination therapy with other medications?
No, there are chances that Venetoclax may interact with certain drugs. It is crucial to inform your healthcare expert if you are already taking any medication.
Marketer Details
Abbvie
Author Details
Written By:
Nonish Sharma
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Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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