Soliris 300mg Injection (Eculizumab)
Prescription RequiredManufactured By
Alexion
Pack Of
1
Salt Composition
Eculizumab
Storage
Keep in cold place
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Up to 60% Discounts
Overview
Soliris 300mg Injection is a prescription-based medicine used in the treatment of blood-related disorders. They include myasthenia gravis, neuromyelitis optica spectrum disorder, haemolytic uremic syndrome, and paroxysmal nocturnal hemoglobinuria. The active ingredient of the Soliris is eculizumab, which belongs to the drug class of monoclonal antibodies. It works by binding to and blocking the complement protein C5, preventing the formation of the membrane attack complex that can damage healthy blood cells and tissues. Eculizumab injection is usually given in combination with another medicine to increase the efficacy of the treatment.
The injection is administered as an intravenous infusion by a qualified doctor in a hospital or clinical setting. The doctor determines the dosage of the Eculizumab 300mg injection according to the type of cancer, treatment regimen, age, and overall health of the patient. It should not be self-administered. Patients are advised not to change the dosage and timings prescribed by the doctors because it can cause severe side effects.
Common side effects include headache, nausea, diarrhea, respiratory tract infections, abdominal discomfort, and infusion-related reactions. A few patients can undergo severe side effects, including serious fever, severe headache, neck stiffness, confusion, and rash. Most of the Eculizumab 300mg injection side effects can leave when the body adapts to the medicine. However, if any side effects persist, inform your doctor immediately.
Meningococcal vaccination is required before treatment. Patients must list any active infection, immune-system disorder, medicines, supplements, and herbal products that they are taking. The Eculizumab 300mg injection must be used under medical oversight or medical supervision only. Attend regular tests and follow-ups to monitor the medicine response and reduce side effects. Before making any adjustments, changing the dose, or stopping the treatment, consult with your doctor to maximize the benefit.
Indication
Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer
Side Effects
The human body shows undesired symptoms after taking Soliris 300mg Injection (Eculizumab). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Common Side Effects
- Some of the common side effects of Soliris Injection are mentioned below:
- ● Rash
- ● Fever
- ● Chills
- ● Fatigue
- ● Diarrhea
- ● Headache
- ● Muscles pain
- ● Constipation
- ● Abdominal pain
- ● Nausea and vomiting
- ● Difficulty in breathing
- ● Infection at injection site
Serious Side Effects
- ● Urinary tract infection
How To Use
Eculizumab 300mg Injection (Soliris) is a prescription-based drug. It is advised to take this injection after consulting your healthcare expert. This medicine should be given intravenously by an experienced nurse or doctor. Please do not self-administer.
Reference
● Ringelstein, M., Asseyer, S., Lindenblatt, G., Fischer, K., Pul, R., Skuljec, J., ... & German Neuromyelitis Optica Study Group (NEMOS). (2024). Eculizumab use in neuromyelitis optica spectrum disorders: routine clinical care data from a European cohort. Neurology, 103(9), e209888.
● Davis, J. (2008). Eculizumab. American Journal of Health-System Pharmacy, 65(17), 1609-1615.
● Dhillon, S. (2018). Eculizumab: a review in generalized myasthenia gravis. Drugs, 78(3), 367-376.
● Hillmen, P., Young, N. S., Schubert, J., Brodsky, R. A., Socié, G., Muus, P., ... & Luzzatto, L. (2006). The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria. New England Journal of Medicine, 355(12), 1233-1243.
● Wijnsma, K. L., Ter Heine, R., Moes, D. J. A., Langemeijer, S., Schols, S. E., Volokhina, E. B., ... & Brüggemann, R. J. (2019). Pharmacology, pharmacokinetics and pharmacodynamics of eculizumab, and possibilities for an individualized approach to eculizumab. Clinical pharmacokinetics, 58(7), 859-874.
Safety Advice
- ● Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Eculizumab 300mg Injection (Soliris). It is advised to consult your doctor for further information.
- ● Pregnancy: Soliris 300mg Injection (Eculizumab) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- ● Breastfeeding: Eculizumab 300mg Injection (Soliris) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- ● Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Eculizumab 300mg Injection (Soliris).
- ● Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Soliris 300mg Injection (Eculizumab).
- ● Liver: Inform your doctor before starting Soliris 300mg Injection (Eculizumab) if you have liver disease to avoid any serious side effects
FAQs
What disease is treated using Soliris 300mg Injection (Eculizumab)?
Soliris 300mg Injection is a prescription-based medicine used to treat Myasthenia Gravis; Neuromyelitis Optica Spectrum Disorder; Hemolytic Uremic Syndrome; Paroxysmal Nocturnal Hemoglobinuria.
What type of drug is Soliris?
Soliris is a selective immunosuppressant monoclonal antibody which is a type of immune drug.
Can Eculizumab 300mg Injection (Soliris) work as combination drug?
Yes, Eculizumab 300mg Injection is used as combination drug to increase the treatment effectiveness.
Is it safe to give Soliris to children?
Yes, it is considered safe for both children and adults. It is advised to take consultation with your doctor before taking it.
What is the correct way to take Eculizumab 300mg Injection (Soliris)?
This medicine should be given intravenously by an experienced nurse or doctor. Please do not self-administer.
Marketer Details
Alexion
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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