Rituxy 500mg/50ml Injection (Rituximab)
Prescription RequiredManufactured By
Glenmark
Pack Of
1
Salt Composition
Rituximab
Storage
Keep in cold place
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Overview
Rituxy 500mg Injection is a monoclonal anibody based anticancer injection injection prescribed by the doctor to treat non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL), rheumatoid arthritis (with methotrexate), granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and pemphigus vulgaris.
Rituxy Injection contains Rituximab, lab made antibody that specifically binds to CD20 antigen on pre or mature B lymphocytes to trigger antibody-dependent cellular cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC), and direct apoptosis in cancer cells. As a result, reduce cancer cell growth and proliferation.
Indication
Cancer Medicines, Lymphoma Cancer
Side Effects
Like any other chemical based medication, it also has certain common side effects. Consult your doctor, if side effects persist for longer period of time.
Common Side Effects of Rituximab 500mg Injection (Rituxy) are :
● Pain in your muscles, bones, and joints Headache
● Headache
● Cough
● Diarrhea
● Nausea
● Weakness
● Itchy skin or rash
● Shortness of breath
● Decreased appetite
● Infection in the nose or throat
● Fever
● Pain in your muscles, bones, and joints
● Hair Loss
● Constipation
● Swelling
● Mouth Sores
● Infusion reactions
● Night Sweats
● Abdominal pain
Serious Side Effects
- Serious Side Effects:
- ● Severe Skin Reactions
- ● Pneumonitis
- ● Severe Allergic reaction
- ● Bone Marrow Supression
- ● Gastrointestinal Perforation
- ● Tumor lysis Syndrome
- ● Hepatitis B Reactivation
- ● Cardiac Arrythmias
How To Use
Rituxy 50ml Injection is administered intravenously (In Veins) by a doctor or an experienced nurse. It is advice not to self administer the injection on your own.
For personalized dosage ask your doctor about the same.As Dosage is entirely based on the body surface area, type of cancer, its stage as well as patient's overall health.
Reference
● Weiner, G. J. (2010, April). Rituximab: mechanism of action. In Seminars in hematology (Vol. 47, No. 2, pp. 115-123). WB Saunders.
● Pescovitz, M. D. (2006). Rituximab, an anti-cd20 monoclonal antibody: history and mechanism of action. American journal of transplantation, 6(5), 859-866.
● Pierpont, T. M., Limper, C. B., & Richards, K. L. (2018). Past, present, and future of rituximab—the world’s first oncology monoclonal antibody therapy. Frontiers in oncology, 8, 163.
● Van der Kolk, L. E., Grillo‐Lopez, A. J., Baars, J. W., Hack, C. E., & Van Oers, M. H. J. (2001). Complement activation plays a key role in the side‐effects of rituximab treatment. British journal of haematology, 115(4), 807-811.
Safety Advice
- 1. It is generally advice to avoid or limit alcohol consumption. Alcohol can affect the working mechanism of Rituximab 500mg Injection (Rituxy) as well as there are possibility of reducing effectiveness. For more details and approvals, Consult your Doctor.
- 2. Rituxy 50ml Injection is not prescribed or allowed at the time of pregnancy. It causes embryo-fetal toxicity.Consult your doctor in case of accidental pregnancy, treatment or further risks.
- 3. In general there is no data related to Rituxy Injection and its effect on breast feeding. But it is generally not advisable during the medication course. Consult your Doctor for more information.
- 4. It is advisable not to drive, as you may feel dizzy and can come across blurred vision after taking Rituximab 500mg Injection (Rituxy) .
- 5. Share your medical history details related to kidney cancer or any other disease with your doctor before taking Rituxy 500mg Injection.
- 6. Notify your doctor about any liver disease or infection before starting Rituxy 500mg/50ml Injection course. As it can cause serious liver damage.
FAQs
What is the use of Rituximab 500mg/50mg Injection (Rituxy)?
Rituximab 500mg/50mg Injection (Rituxy) is mainly used to treat non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL), rheumatoid arthritis (with methotrexate), granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and pemphigus vulgaris.
How to administer Rituxy 500mg/50ml Injection?
Rituxy 50ml Injection should be administered intravenously by a doctor or an experienced nurse. Patient should not self administer the injection.
What should I do if I miss the Rituxy 500mg/50ml Injection?
If you miss a Rituxy 500mg/50ml Injection dose, contact your doctor or healthcare provider immediately to reschedule; do not skip the dose, as they will determine the appropriate timing based on your treatment schedule and condition.
Are there any serious side effects of Rituximab 500mg/50mg Injection (Rituxy)?
Yes, Serious side effects of Rituximab 500mg/50mg Injection (Rituxy) include tumor lysis syndrome, progressive multifocal leukoencephalopathy (PML), hepatitis B reactivation, severe infections etc.These side effects require immediate medical attention.
Can a Pregnant women consume Rituxy 500mg/50ml Injection?
Rituxy 500mg Injection is not safe for baby during pregnancy. Consult your doctor beforehand.
Marketer Details
Glenmark
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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