Piqray 150mg Tablet (Alpelicib)
Prescription RequiredManufactured By
Novartis
Pack Of
28
Salt Composition
Alpelicib
Storage
Keep in cold place
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ALL SUBSTITUTES
Alpesib 150mg Tablet
Overview
Piqray 150mg Tablet is a prescription-based anticancer medicine used in the treatment of breast cancer, sickle cell anemia, prostate cancer, blood cancer (acute lymphocytic leukemia), soft tissue sarcoma and Hodgkin’s disease. The active ingredient of the Piqray is Alpelicib which belongs to the drug class of gonadotropin-releasing hormone (GnRH) receptor antagonists.
This drug works through blocking the function of a particular protein found in some cancer cells. This helps prevent the growth and spread of the cancer cells. Alpelicib Tablet is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
Indication
Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer
Side Effects
The human body shows undesired symptoms after taking Piqray 150mg Tablet (Alpelicib). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Common Side Effects
- Some of the common side effects of Piqray Tablet are mentioned below:
- ● Chills
- ● Rash
- ● Fever
- ● Fatigue
- ● Hair loss
- ● Diarrhea
- ● Joint pain
- ● Headache
- ● Depression
- ● Constipation
- ● Stomach Pain
- ● Nausea & Vomiting
- ● High blood pressure
- ● Increased blood sugar level
Serious Side Effects
- ● Increased creatinine level in blood
- ● Low level of hemoglobin in blood
- ● Low level of Potassium in the blood
- ● Increased level of alanine aminotransferase
- ● Increased level of gamma-glutamyltransferase
How To Use
Alpelicib 150mg Tablet (Piqray) is a prescription-based anticancer drug that should be administered orally. Dosage and the duration determined as per stage & type of cancer and the patients’ health condition.
This tablet should be swallowed as a whole with water. Don't crush, chew, or break the tablet. It should be taken with food. Never skip a dose or double dose.
Reference
● Xu, H., Chen, K., Shang, R., Chen, X., Zhang, Y., Song, X., ... & Chen, X. (2021). Alpelisib combination treatment as novel targeted therapy against hepatocellular carcinoma. Cell Death & Disease, 12(10), 920.
● Armaghani, A. J., & Han, H. S. (2020). Alpelisib in the treatment of breast cancer: a short review on the emerging clinical data. Breast Cancer: Targets and Therapy, 251-258.
● André, F., Ciruelos, E., Rubovszky, G., Campone, M., Loibl, S., Rugo, H. S., ... & Juric, D. (2019). Alpelisib for PIK3CA-mutated, hormone receptor–positive advanced breast cancer. New England Journal of Medicine, 380(20), 1929-1940.
● Singh, S., Bradford, D., Li, X., Mishra-Kalyani, P. S., Shen, Y. L., Wang, L., ... & Donoghue, M. (2024). FDA approval summary: alpelisib for PIK3CA-related overgrowth spectrum. Clinical Cancer Research, 30(1), 23-28.
● André, F., Ciruelos, E., Rubovszky, G., Campone, M., Loibl, S., Rugo, H. S., ... & Juric, D. (2019). Alpelisib for PIK3CA-mutated, hormone receptor–positive advanced breast cancer. New England Journal of Medicine, 380(20), 1929-1940.
Safety Advice
- • Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Piqray 150mg Tablet (Alpelicib). It is advised to consult your doctor for further information.
- • Pregnancy: Alpelicib 150mg Tablet (Piqray) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- • Breastfeeding: Piqray 150mg Tablet (Alpelicib) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- • Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Piqray 150mg Tablet (Alpelicib).
- • Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Piqray 150mg Tablet (Alpelicib).
- • Liver: Inform your doctor before starting Alpelicib 150mg Tablet (Piqray) if you have liver disease to avoid any serious side effects.
FAQs
What are the dosage and duration of taking Alpelicib 150mg Tablet (Piqray)?
Your healthcare expert decides the doses and how they should be taken. This medicine is taken orally with or without food as per the doctor's advice. It should be consumed at the same time each day for better results. It is recommended not to crush, chew, or split the Tablet take them as a whole.
What actions should be taken if I forget to take Piqray 150mg Tablet (Alpelicib)?
It is advised not to miss any scheduled dosage of this medicine. In case you miss a dose, consult your doctor immediately. Don't overdose to compensate for the missed one.
Does Alpelicib 150mg Tablet (Piqray) have any effect on fertility?
It may affect the fertility in both. So, consult your doctor in prior if you are planning to be pregnant in the future.
Why is it important to use contraceptive pills while on the treatment of Alpelicib 150mg Tablet (Piqray)?
Alpelicib Tablet can pass through semen, so it is considered unsafe to be pregnant during treatment. It is advised to use reliable methods of birth control and contraceptive pills to avoid pregnancy while under treatment.
Is it safe to take Piqray 150mg Tablet (Alpelicib) to kidney patients?
Healthcare experts will recommend the dose and duration for kidney patients. It might interact and have certain consequences, though. So, it is advised to consult before taking this medicine.
Marketer Details
Novartis
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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