Lumakras 120mg Tablet (Sotorasib)
Prescription RequiredManufactured By
Amgen
Pack Of
240
Salt Composition
Sotorasib
Storage
Keep in cold place
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ALL SUBSTITUTES
Sotoxen 120mg Capsule
Overview
Lumakras 120mg Tablet is a prescription-based anticancer medicine used in the treatment of non-small cell lung cancer (NSCLC) in adults. The active ingredient of the Lumakras is Sotorasib which belongs to the drug class of KRAS inhibitors. The growth of cancer cells is uncontrollable and abnormal in the human body.
It is difficult to diagnose cancer in the early stages as there are no noticeable symptoms. When diagnosed in advanced stages, only the symptoms of the disease can be reduced. Sotorasib Tablet (Lumakras) is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
Indication
Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer
Side Effects
The human body shows undesired symptoms after taking Sotorasib 120mg Tablet (Lumakras). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Some of the common side effects of Lumakras Tablet are mentioned below:
● Diarrhea
● Nausea
● Tiredness
● Cough
● Liver problems
● Muscle or Bone pain
● Lung and breathing problems
● Changes in liver function tests
How To Use
Lumakras 120mg Tablet (Sotorasib) is a prescription-based anticancer drug that should be administered orally. It is advised to take this Tablets after consulting your healthcare expert. This tablet should be swallowed as a whole with water. Don't crush, chew, or break it. It can be taken with or without food. Never skip a dose or double dose.
Reference
● Nakajima, E. C., Drezner, N., Li, X., Mishra-Kalyani, P. S., Liu, Y., Zhao, H., ... & Singh, H. (2022). FDA approval summary: sotorasib for KRAS G12C-mutated metastatic NSCLC. Clinical Cancer Research, 28(8), 1482-1486.
● Lee, A. (2022). Sotorasib: a review in KRAS G12C mutation-positive non-small cell lung cancer. Targeted Oncology, 17(6), 727.
● Skoulidis, F., Li, B. T., Dy, G. K., Price, T. J., Falchook, G. S., Wolf, J., ... & Govindan, R. (2021). Sotorasib for lung cancers with KRAS p. G12C mutation. New England Journal of Medicine, 384(25), 2371-2381.
● Hong, D. S., Fakih, M. G., Strickler, J. H., Desai, J., Durm, G. A., Shapiro, G. I., ... & Li, B. T. (2020). KRASG12C inhibition with sotorasib in advanced solid tumors. New England Journal of Medicine, 383(13), 1207-1217.
● Blair, H. A. (2021). Sotorasib: first approval. Drugs, 81(13), 1573-1579.
Safety Advice
- • Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Sotorasib 120mg Tablet (Lumakras). It is advised to consult your doctor for further information.
- • Pregnancy: Lumakras 120mg Tablet (Sotorasib) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- • Breastfeeding: Lumakras 120mg Tablet (Sotorasib) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- • Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Sotorasib 120mg Tablet (Lumakras).
- • Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Lumakras 120mg Tablet (Sotorasib).
- • Liver: Inform your doctor before starting Lumakras 120mg Tablet (Sotorasib) if you have liver disease to avoid any serious side effects
FAQs
Why do doctors prescribe Sotorasib 120mg Tablet (Lumakras)?
This medicine is given to people diagnosed with non-small cell lung cancer (NSCLC) in adults. This cancer is the result of mutation in the gene KRAS G12C.
What is the right way of taking the Lumakras 120mg Tablet (Sotorasib)?
Lumakras is taken orally once a day, with or without food as per doctor's advice. It is consumed at the same time each day for better results. It is recommended not to crush, chew, or split the Tablets, take it as a whole.
What are the commonly observed side effects of Lumakras 120mg Tablet (Sotorasib)?
The most common side effects of this medicine include diarrhea, nausea, liver problems, fatigue, and cough. It is advised to go for regular liver function tests to examine the liver function.
Who should avoid taking Sotorasib 120mg Tablet (Lumakras)?
People diagnosed with severe liver disorders and without the KRAS G12C mutation are advised by healthcare professionals to avoid taking this medicine.
Can Lumakras 120mg Tablet (Sotorasib) be given in combination therapy with other medications?
There are chances that Lumakras may interact with certain drugs, mainly in cases of CYP3A inhibitors or inducers. It is crucial to inform your healthcare expert if you're already taking any medication.
Marketer Details
Amgen
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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