Sotoxen 120mg Tablet (Sotorasib)
Sotoxen 120mg Tablet (Sotorasib)

Sotoxen 120mg Tablet (Sotorasib)

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Manufactured By

Everest

Pack Of

56

Salt Composition

Sotorasib

Storage

Keep in cold place

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Lumakras 120mg Tablet

Lumakras 120mg Tablet

Overview

Sotoxen 120mg Tablet is a prescription-based anticancer medicine used in the treatment of non-small cell lung cancer (NSCLC) in adults. The active ingredient of Sotoxen is Sotorasib, which belongs to the drug class of KRAS inhibitors. It works by blocking the abnormal KRAS G12C protein found in some cancer cells. This can reduce the abnormal signals that promote cancer-cell growth and survival, helping to slow the progression of the disease. It is difficult to diagnose cancer in the early stages, as there are no noticeable symptoms. When diagnosed in advanced stages, only the symptoms of the disease can be reduced. Sotorasib tablets are usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.

The tablet must be taken orally and swallowed whole with water and should not be crushed, chewed, or opened. The prescribed dose and duration of the Sotorasib 120mg tablet depend on the patient's condition and response to treatment. It can also be taken with or without food. Patients are advised not to change the dosage and timings prescribed by the doctors because it can cause severe side effects.

Common side effects include diarrhea, nausea, muscle or bone pain, cough, tiredness, decreased appetite, and changes in liver function tests. A few patients can undergo severe side effects, including liver toxicity, interstitial lung disease or pneumonitis, and severe gastrointestinal problems. Most of the Sotorasib 120mg tablet side effects can leave when the body adapts to the medicine. However, report to your doctor if you experience serious side effects.

Pregnant or breastfeeding women should consult their healthcare professional before using the medicine. Patients should promptly report yellowing of the skin or eyes, dark urine, or severe or persistent diarrhea. Patients must list all medicines, supplements, and herbal products that they are taking. The Sotorasib 120mg tablet must be used under medical oversight or medical supervision only. Attend regular tests and follow-ups to monitor the medicine response and reduce side effects. Before making any adjustments, changing the dose, or stopping the treatment, consult with your doctor to maximize the benefit.

Quick Product Facts

FieldPublication wording
Brandsotoxen
Generic / Active IngredientSotorasib
Strength40
Dosage FormCapsule
Manufacturer / MarketerEverest
Pack Size56
Prescription RequiredYes
Therapeutic CategoriesCancer Medicines
UsesLung Cancer

Uses and Indications

Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer

Side Effects of Sotoxen 120mg Tablet

The human body shows undesired symptoms after taking Sotorasib 120mg Tablet (Sotoxen). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Some of the common side effects of Sotoxen Tablet are mentioned below:
● Diarrhea
● Nausea
● Tiredness
● Cough
● Liver problems
● Muscle or Bone pain
● Lung and breathing problems
● Changes in liver function tests

Sotoxen 120mg Tablet Dosage and How To Take It

Sotorasib 120mg Tablet (Sotoxen) is a prescription-based anticancer drug that should be administered orally. It is advised to take this Tablets after consulting your healthcare expert. This tablet should be swallowed as a whole with water. Don't crush, chew, or break it. It can be taken with or without food. Never skip a dose or double dose.

Safety Advice for Sotoxen 120mg Tablet

  • • Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Sotoxen Tablet (Sotorasib). It is advised to consult your doctor for further information.
  • • Pregnancy: Sotorasib 120mg Tablet (Sotoxen) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
  • • Breastfeeding: Sotoxen 120mg Tablet (Sotorasib) is probably not safe if you're breastfeeding. Kindly consult your doctor.
  • • Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Sotorasib 120mg Tablet (Sotoxen).
  • • Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Sotoxen 120mg Tablet (Sotorasib).
  • • Liver: Inform your doctor before starting Sotoxen 120mg Tablet (Sotorasib) if you have liver disease to avoid any serious side effects.

FAQs About Sotoxen 120mg Tablet

Why do doctors prescribe Sotoxen 120mg Tablet (Sotorasib)?

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This medicine is given to people diagnosed with non-small cell lung cancer (NSCLC) in adults. This cancer is the result of mutation in the gene KRAS G12C.

What is the right way of taking the Sotorasib 120mg Tablet (Sotoxen)?

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Sotoxen is taken orally once a day, with or without food as per doctor's advice. It is consumed at the same time each day for better results. It is recommended not to crush, chew, or split the Tablets, take it as a whole.

What are the commonly observed side effects of Sotoxen 120mg Tablet (Sotorasib)?

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The most common side effects of this medicine include diarrhea, nausea, liver problems, fatigue, and cough. It is advised to go for regular liver function tests to examine the liver function.

Who should avoid taking Sotorasib 120mg Tablet (Sotoxen)?

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People diagnosed with severe liver disorders and without the KRAS G12C mutation are advised by healthcare professionals to avoid taking this medicine.

Can Sotoxen 120mg Tablet (Sotorasib) be given in combination therapy with other medications?

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There are chances that Sotoxen may interact with certain drugs, mainly in cases of CYP3A inhibitors or inducers. It is crucial to inform your healthcare expert if you're already taking any medication.

References

● Nakajima, E. C., Drezner, N., Li, X., Mishra-Kalyani, P. S., Liu, Y., Zhao, H., ... & Singh, H. (2022). FDA approval summary: sotorasib for KRAS G12C-mutated metastatic NSCLC. Clinical Cancer Research, 28(8), 1482-1486.
● Lee, A. (2022). Sotorasib: a review in KRAS G12C mutation-positive non-small cell lung cancer. Targeted Oncology, 17(6), 727.
● Skoulidis, F., Li, B. T., Dy, G. K., Price, T. J., Falchook, G. S., Wolf, J., ... & Govindan, R. (2021). Sotorasib for lung cancers with KRAS p. G12C mutation. New England Journal of Medicine, 384(25), 2371-2381.
● Hong, D. S., Fakih, M. G., Strickler, J. H., Desai, J., Durm, G. A., Shapiro, G. I., ... & Li, B. T. (2020). KRASG12C inhibition with sotorasib in advanced solid tumors. New England Journal of Medicine, 383(13), 1207-1217.
● Blair, H. A. (2021). Sotorasib: first approval. Drugs, 81(13), 1573-1579.

Marketer Details

Everest

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Author Details

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Written By:

Nonish Sharma

I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More


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Reviewed By:

Vaibhav Shakya

Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More

Last Updated: 14 Sept 2026 | 11:59 am (IST)

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