Ledifos Tablet (Ledipasvir (90mg) + Sofosbuvir (400mg))
Prescription RequiredManufactured By
Hetero
Pack Of
28
Salt Composition
Ledipasvir (90mg) + Sofosbuvir (400mg)
Storage
Keep in cold place
ALL SUBSTITUTES
Hepcvir L Tablet
Ledviclear Tablet
Myhep Lvir Tablet
Overview
Ledifos Tablet is an antiviral medicine that is a combination of two antiviral medicines such as Ledipasvir (90mg) and Sofosbuvir (400mg). It is prescribes to treat chronic hepatitis C virus (HCV) infection.
It works by reducing the viral load in the body and eliminating viruses from the blood over time. It should be taken in dose and duration as advice by the doctor. Don't take more than the recommended dose. Default overview text
Quick Product Facts
| Field | Publication wording |
|---|---|
| Brand | ledifos |
| Generic / Active Ingredient | Ledipasvir (90mg) + Sofosbuvir (400mg) |
| Strength | 90 |
| Dosage Form | Tablet |
| Manufacturer / Marketer | Hetero |
| Pack Size | 28 |
| Prescription Required | Yes |
| Therapeutic Categories | Hepatitis Medicines |
| Uses | hepatitis |
Uses and Indications
Hepatitis C
Side Effects of Ledifos Tablet
Ledifos Tablet(Ledipasvir (90mg) + Sofosbuvir (400mg)) is a strong antiviral medicine that may show certain adverse while manageable impact on the body during the treatment. As these effects resolve on their own without any special medical attention. However, if you ever experience serious or unusual side effects contact your healthcare professional immediately.
Some common side effects of Resof-L include:
● Nausea
● Vomiting
● Diarrhea
● Stomach pain
● Difficulty in falling asleep
● Irritability
● Chest pain
● Decreased appetite
● Muscle pain and cramps
Common or Clinically Frequent Side Effects
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Ledifos Tablet Dosage and How To Take It
Doctor determines the dosage and duration of Ledifos Tablet(Ledipasvir (90mg) + Sofosbuvir (400mg)) as per the severity of the infection as well as age & overall health condition of the patients. Swallow it as a whole with water and don't chew, crush or break the tablet. This tablet may be taken with or without food. In case of an overdose of this tablet, contact your doctor or any healthcare provider and seek medical attention immediately.
Safety Advice for Ledifos Tablet
- ● Alcohol: Avoid the consumption of alcohol while taking Ledifos Tablet(Ledipasvir (90mg) + Sofosbuvir (400mg)), as alcohol can decrease the effectiveness of the medicine as well as worsen the symptoms
- ● Pregnancy: Ledifos Tablet is safe to use during pregnancy, if prescribed by the doctor. No dosage adjustment is necessary for this tablet as limited data is available that shows significant risk.
- ● Breastfeeding: Ledifos Tablet(Ledipasvir (90mg) + Sofosbuvir (400mg)) is safe to use while breastfeeding, if prescribed by the doctor. No dosage adjustment is necessary for this tablet as limited data is available that shows significant risk.
- ● Driving: Ledifos Tablet may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving.
- ● Kidney: Share your medical history with the doctor before starting the Ledifos Tablet. Do not take it without consulting a doctor if you have any kidney related issue.
- ● Liver: Ledifos Tablet(Ledipasvir (90mg) + Sofosbuvir (400mg)) is safe for use in liver disease if prescribed by the doctor. No dosage adjustment is necessary for this Tablet.
FAQs About Ledifos Tablet
Is it safe to take the Ledifos Tablet(Ledipasvir (90mg) + Sofosbuvir (400mg)) during pregnancy or breastfeeding?
Consumption of Ledifos during pregnancy & breastfeeding is considered to be safe. However, it is necessary to consult with a doctor in both cases.
Can I drive after taking Ledifos Tablet?
It is unsafe to drive after taking treatment with this medicine as lack of concentration or dizziness is the common side effect of Ledifos Tablet(Ledipasvir (90mg) + Sofosbuvir (400mg)).
Is it safe to take other medicine with Ledifos Tablet?
As Ledifos(Ledipasvir (90mg) + Sofosbuvir (400mg)) can interact with some medicine. It is advisable to inform your doctor about any medicine you are taking.
What are the common side effects of Ledifos Tablet(Ledipasvir (90mg) + Sofosbuvir (400mg))?
There are some common yet manageable side effects of taking Ledifos that include diarrhea, headache, nausea, vomiting, anemia, etc.
References
● Mastanamma, S. K., Chandini, S. K., Reehana, S. K., & Saidulu, P. (2018). Development and validation of stability indicating RP-HPLC method for the simultaneous estimation of Sofosbuvir and Ledipasvir in bulk and their combined dosage form. Future journal of pharmaceutical sciences, 4(2), 116-123.
● Gane, E. J., Hyland, R. H., An, D., Svarovskaia, E., Pang, P. S., Brainard, D., & Stedman, C. A. (2015). Efficacy of ledipasvir and sofosbuvir, with or without ribavirin, for 12 weeks in patients with HCV genotype 3 or 6 infection. Gastroenterology, 149(6), 1454-1461.
● Naggie, S., Cooper, C., Saag, M., Workowski, K., Ruane, P., Towner, W. J., ... & Sulkowski, M. (2015). Ledipasvir and sofosbuvir for HCV in patients coinfected with HIV-1. New England Journal of Medicine, 373(8), 705-713.
● Lawitz, E., Poordad, F. F., Pang, P. S., Hyland, R. H., Ding, X., Mo, H., ... & Membreno, F. E. (2014). Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial. The Lancet, 383(9916), 515-523.
● Keating, G. M. (2015). Ledipasvir/Sofosbuvir: a review of its use in chronic hepatitis C. Drugs, 75(6), 675-685.
Marketer Details
Hetero
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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