Kryxana 200mg Tablet (Ribociclib)
Prescription RequiredManufactured By
Novartis
Pack Of
21
Salt Composition
Ribociclib
Storage
Keep in cold place
Fast Delivery
Easy Returns
Secure Payments
Up to 60% Discounts
ALL SUBSTITUTES
Kisqali 600mg Tablet
Overview
Kryxana 200mg Tablet is a prescription-based anticancer medicine used in the treatment of hormone receptor-positive (HR+), HER2-negative breast cancer, including advanced or metastatic breast cancer. The active ingredient is ribociclib, which belongs to the class known as cyclin-dependent kinase (CDK) 4/6 inhibitors. This works by inhibiting the CDK4 and CDK6 proteins that help in the growth and multiplication of cancer cells. Therefore, after blocking these proteins, it can lead to decreased cancer progression and division of cancerous cells. This is usually given in combination with other anticancer or hormone therapy medicine to improve the effectiveness of treatment.
The tablet is taken orally and exactly as prescribed by the doctor. The tablet must be swallowed as whole with water and should not be crushed, chewed, or broken. It is usually taken with or without food. Kryxana 200mg Tablet is given once daily, and a doctor decides the dose and timings according to the patient's condition, combination therapy, clinical response, and stage of cancer. Patients are advised not to change the dosage because it can lead to severe side effects.
Common side effects can include low levels of white blood cells, infections, tiredness, nausea, vomiting, diarrhea, constipation, headache, loss of appetite, hair loss, and abnormal liver-function test results. Most of the Kryxana 200mg tablet side effects can leave when the body adapts to the medicine. However, report to your doctor if you experience serious side effects.
Patients must list all medicines, supplements, and herbal products that they are taking. The Kryxana 200mg Tablet must be used under medical oversight or medical supervision only. Attend regular tests and follow-ups to monitor the medicine response and reduce side effects. Before making any adjustments, changing the dose, or stopping the treatment, consult with your doctor to maximize the benefit.
Indication
Breast Cancer
Side Effects
The human body shows undesired symptoms after taking the Kryxana 200mg tablet (ribociclib). Usually, they disappear with time as the body adjusts to the medicine. These side effects do not need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Common side effects
● Neutropenia
● Nausea
● Fatigue
● Diarrhea
● Vomiting
● Headache
● Alopecia
● Constipation
● Hair loss
● Skin rash
● Low white blood cell
● Infections
● Tiredness
● Low blood sugar
Serious side effects
● QT Prolongation
● Liver Toxicity
● Lung Inflammation
● Severe Skin Reactions
How To Use
Kryxana 200mg Tablet (Ribociclib) is a prescription-based anticancer medicine. It should be taken only after consulting your healthcare doctor. This medicine is taken orally with or without food, usually once daily to maintain consistency. Swallow the tablets whole with water and do not chew or crush them.
Missed Doses
● Take the missed dose as soon as you remember but ensure that it is not close to the next scheduled dose.
● If it is close to the next dose, skip the dose.
● Avoid overdose of the medicine by consuming two simultaneously.
● If you vomit the dose, do not consume the dose at the same day.
Reference
● Raedler, L. A. Kisqali (Ribociclib): Second CDK4/CDK6 Inhibitor Approved for Postmenopausal Women with HR-Positive, HER2-Negative Advanced Breast Cancer.
● Mann, J. E. (2017). Ribociclib (Kisqali®). Oncology Times, 39(16), 30.
● Hortobagyi, Gabriel N., et al. "Ribociclib as first-line therapy for HR-positive, advanced breast cancer." New England journal of medicine 375.18 (2016): 1738-1748.
● Syed, Y. Y. (2017). Ribociclib: first global approval. Drugs, 77(7), 799-807.
● Hortobagyi, Gabriel N., et al. "Overall survival with ribociclib plus letrozole in advanced breast cancer." New England Journal of Medicine 386.10 (2022): 942-950.
● Kwapisz, D. (2017). Cyclin-dependent kinase 4/6 inhibitors in breast cancer: palbociclib, ribociclib, and abemaciclib. Breast cancer research and treatment, 166(1), 41-54.
Safety Advice
- ● Alcohol: Avoid alcohol while taking Kryxana 200mg Tablet (Ribociclib) because both the medication and alcohol are processed by the liver and can cause fatigue or nausea. Consult your doctor for further advise.
- ● Pregnancy: Ribociclib 200mg Tablet (Kryxana) may harm the unborn baby. Inform your doctor if you are pregnant or planning pregnancy. Effective contraception is recommended during treatment and for at least 3 weeks after the last dose.
- ● Breastfeeding: Do not breastfeed while taking Kryxana 200mg Tablet (Ribociclib) and for at least 3 weeks after the last dose.
- ● Driving: Use caution while driving or operating machinery; if you experience tiredness, dizziness, or other symptoms, inform your doctor immediately.
- ● Kidney: Inform your doctor if you have kidney disease before taking Ribociclib 200mg Tablet (Kryxana), as dose adjustment may be required in severe kidney issues.
- ● Liver: Inform your doctor if you have liver disease before starting Kryxana 200mg Tablet (Ribociclib), as dose adjustment may be required in severe liver impairment
FAQs
What is Ribociclib 200mg Tablet (Kryxana) used for?
Kryxana 200mg Tablet is used to treat hormone receptor-positive (HR+), HER2-negative advanced or metastatic breast cancer.
Can Kryxana 200mg Tablet (Ribociclib) cause low blood sugar?
Yes, the Kryxana 200mg tablet may cause low blood sugar levels as a side effect. Consult your doctor if you experience symptoms such as dizziness, sweating, and shakiness.
Can Kryxana 200mg Tablet be used in combination with other medicines?
Yes, Kryxana is generally used in combination with hormonal anticancer medicines, such as an aromatase inhibitor or fulvestrant.
How should Kryxana 200mg Tablet (Ribociclib) be taken?
Kryxana is usually swallowed as whole with water and taken once daily for 21 consecutive days, followed by a 7-day break, as directed by your doctor.
What precautions should I take while using the Ribociclib 200mg Tablet (Kryxana)?
Regular blood tests, liver-function tests, and ECG monitoring may be required during treatment. Inform your doctor about all medicines you are taking.
Marketer Details
Novartis
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
Want to know More
Check our Editor Policy
Disclaimer
Globanspharma main goal is to ensure that its consumers get correct, authentic, and reliable information that has been examined by medical professionals. This website's content has only been created for informational purposes. However, this is not meant to replace the medical advice and treatment given by a qualified physician. The information presented herein may not cover everything about particular lab tests, medicines, and health conditions, all possible side effects, and warnings. Please discuss all your queries related to any medication and illness with your doctor. We intend to support and maintain the doctor-patient relationship, not to substitute it or take its place.
