Iclusig 15mg Tablet (Ponatinib)
Prescription RequiredManufactured By
Takeda
Pack Of
30
Salt Composition
Ponatinib
Storage
Keep in cold place
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ALL SUBSTITUTES
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Overview
Iclusig 15mg Tablet is a prescription-based anticancer medicine used to treat types of blood cancer in adults such as with chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). The active ingredient of the Iclusig is Ponatinib which belongs to the drug class of Tyrosine kinase inhibitor (TKI).
It works by blocking abnormal proteins (such as BCR-ABL) to control the growth and multiplication of cancer cells. Ponatinib Tablet is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
Indication
Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer
Side Effects
The human body shows undesired symptoms after taking Iclusig 15mg Tablet (Ponatinib). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Some of the common side effects of Iclusig Tablet are mentioned below:
● Fainting
● Headache
● Dizziness
● Constipation
● Loss of appetite
● Weight gain
● Blurred vision
● Severe headache
● Slow wound healing
● Palpitations (Irregular Heartbeat)
● Numb/tingling sensation on skin
How To Use
Ponatinib 15mg Tablet (Iclusig) is a prescription-based anticancer drug that should be administered orally. Iclusig is taken orally with or without food as per the doctor's advice.
It is consumed at the same time each day for better results. It is recommended not to crush, chew, or split the tablet, take it as a whole.
Reference
● Price, K. E., Saleem, N., Lee, G., & Steinberg, M. (2013). Potential of ponatinib to treat chronic myeloid leukemia and acute lymphoblastic leukemia. OncoTargets and therapy, 1111-1118.
● Pavlovsky, C., Chan, O., Talati, C., & Pinilla-Ibarz, J. (2018). Ponatinib in the treatment of chronic myeloid leukemia and philadelphia chromosome positive acute lymphoblastic leukemia. Future Oncology, 15(3), 257-269.
● Hoy, S. M. (2014). Ponatinib: a review of its use in adults with chronic myeloid leukaemia or Philadelphia chromosome-positive acute lymphoblastic leukaemia. Drugs, 74(7), 793-806.
● Massaro, F., Molica, M., & Breccia, M. (2018). Ponatinib: a review of efficacy and safety. Current cancer drug targets, 18(9), 847-856.
● Cortes, J. E., Kantarjian, H., Shah, N. P., Bixby, D., Mauro, M. J., Flinn, I., ... & Talpaz, M. (2012). Ponatinib in refractory Philadelphia chromosome–positive leukemias. New England Journal of Medicine, 367(22), 2075-2088.
Safety Advice
- • Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Iclusig 15mg Tablet (Ponatinib). It is advised to consult your doctor for further information.
- • Pregnancy: Ponatinib 15mg Tablet (Iclusig) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- • Breastfeeding: Iclusig 15mg Tablet (Ponatinib) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- • Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Ponatinib 15mg Tablet (Iclusig).
- • Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Iclusig 15mg Tablet (Ponatinib).
- • Liver: Inform your doctor before starting Iclusig 15mg Tablet (Ponatinib) if you have liver disease to avoid any serious side effects
FAQs
Why do doctors prescribe Ponatinib 15mg Tablet (Iclusig)?
This medicine is given to adults diagnosed with different types of blood cancer (chronic myelogenous leukemia-CML, acute lymphoblastic leukemia-ALL).
What is the right way of taking the Ponatinib 15mg Tablet (Iclusig)?
Ponatinib Tablet is taken orally with or without food as per the doctor's advice. It is consumed at the same time each day for better results. It is recommended not to crush, chew, or split the tablet, take it as a whole.
What are the commonly observed side effects of Iclusig 15mg Tablet (Ponatinib)?
The most common side effects of this medicine include Diarrhea, Headache, Tiredness, Mouth sores, Muscle or joint pain, Stomach pain, difficulty breathing and others. It is advised to consult your doctor if these symptoms become unmanageable.
Who should avoid taking Iclusig 15mg Tablet (Ponatinib)?
People diagnosed with severe liver, kidney and other health disorders are advised to consult their healthcare professionals before taking this medicine.
Can the Iclusig 15mg Tablet (Ponatinib) be given in combination therapy with other medications?
Yes, Iclusig can be given in combination therapy with other medications to treat different kinds of cancers and to increase the effectiveness of the treatment.
Marketer Details
Takeda
Author Details
Written By:
Nonish Sharma
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Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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