Geftinat 250mg Tablet (Gefitinib)
Geftinat 250mg Tablet (Gefitinib)

Geftinat 250mg Tablet (Gefitinib)

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Manufactured By

Natco Pharma

Pack Of

30

Salt Composition

Gefitinib

Storage

Keep in cold place

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Overview

Geftinat 250mg Tablet is an anticancer medication used in the treatment of non-small cell lung cancer, especially with endothelial growth factor receptor gene (EGFR) mutation. Such as exon 19 deletions or exon 21 (L858R) substitution mutations. The Geftinat tablet contains 250mg of gefitinib, which belongs to the class of tyrosine kinase inhibitors. Gefitinib inhibits the abnormal EGFR enzyme activity and interrupts the signaling pathways that lead to the proliferation and survival of cancer cells, thereby slowing or stopping tumor growth. A doctor conducts genetic testing to confirm the presence of an EGFR mutation to progress in the therapy.

The tablet must be taken orally and swallowed whole with water and should not be crushed, chewed, or opened. The prescribed dose and duration of the Gefitinib 250mg tablet depend on the patient's condition and response to treatment. It can also be taken with or without food. Patients are advised not to change the dosage and timings prescribed by the doctors because it can cause severe side effects.

Common side effects can include diarrhea, skin rash, dry skin, itching, nausea, vomiting, loss of appetite, mouth sores, and weakness. A few patients can undergo severe side effects, including interstitial lung disease, severe skin reactions, liver problems, and eye disorders. Most of the Gefitinib 250mg tablet side effects can leave when the body adapts to the medicine. However, report to your doctor if you experience serious side effects.

Patients must list all medicines, supplements, and herbal products that they are taking. The Gefitinib 250mg Tablet must be used under medical oversight or medical supervision only. Attend regular tests and follow-ups to monitor the medicine response and reduce side effects. Before making any adjustments, changing the dose, or stopping the treatment, consult with your doctor to maximize the benefit.

Indication

non-small cell lung cancer (NSCLC)

Side Effects

Like any other anticancer medicine, Geftinat 250mg Tablet(Gefitinib 250mg) also shows some side effects, which vary from one person to another according to various health factors. Most of them are mild, and some are serious enough to need immediate medical attention.
Some Common side effects include:
● Diarrhea
● Dry skin
● Loss of appetite
● Nausea
● Rash
● Vomiting
● Weakness
● Weight loss
● Eating disorder
● Allergic reaction
Contact the doctor immediately in case of any unusual or persistent side effects.

How To Use

Doctor determines the dosage and duration of Geftinat 250mg Tablet(Gefitinib 250mg) as per the stage of disease and overall health condition of the patients. Swallow it as a whole with water. Do not chew, crush or break it. This tablet may be taken with or without food. In case of an overdose of this tablet, contact your doctor or any healthcare provider and seek medical attention immediately.

Reference

● Franceschi, E., Cavallo, G., Lonardi, S., Magrini, E., Tosoni, A., Grosso, D., ... & Brandes, A. A. (2007). Gefitinib in patients with progressive high-grade gliomas: a multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO). British journal of cancer, 96(7), 1047-1051.
● Zhao, J., Chen, M., Zhong, W., Zhang, L., Li, L., Xiao, Y., ... & Wang, M. (2013). Cerebrospinal fluid concentrations of gefitinib in patients with lung adenocarcinoma. Clinical lung cancer, 14(2), 188-193.
● Blackhall, F., Ranson, M., & Thatcher, N. (2006). Where next for gefitinib in patients with lung cancer?. The lancet oncology, 7(6), 499-507.
● Namba, Y., Kijima, T., Yokota, S., Niinaka, M., Kawamura, S., Iwasaki, T., ... & Ito, M. (2004). Gefitinib in patients with brain metastases from non–small-cell lung cancer: review of 15 clinical cases. Clinical lung cancer, 6(2), 123-128.
● Baselga, J., Albanell, J., Ruiz, A., Lluch, A., Gascón, P., Guillém, V., ... & Rojo, F. (2005). Phase II and tumor pharmacodynamic study of gefitinib in patients with advanced breast cancer. Journal of Clinical Oncology, 23(23), 5323-5333.

Safety Advice

  • ● Alcohol: Avoid the consumption of alcohol while taking Geftinat 250mg Tablet(Gefitinib 250mg), as alcohol can decrease the effectiveness of the medicine as well as worsen the symptoms
  • ● Pregnancy: Do not take Geftinat 250mg Tablet without consulting the doctor in case of pregnancy, as it is an unsafe to take it during this period.
  • ● Breastfeeding: Breastfeeding women should discuss the potential risks and benefits of the Geftinat 250mg Tablet(Gefitinib 250mg) with their healthcare provider before starting treatment.
  • ● Driving: Geftinat 250mg Tablet may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving.
  • ● Kidney: Share your medical history with the doctor before starting the treatment with Geftinat 250mg Tablet(Gefitinib 250mg). Do not take it without consulting a doctor if you have any liver related issue.
  • ● Liver: Geftinat 250mg Tablet(Gefitinib 250mg) is safe for use in kidney disease if prescribed by the doctor. No dosage adjustment is necessary for this Tablet.

FAQs

What are the uses of Geftinat 250mg Tablet(Gefitinib 250mg)?

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Geftinat 250mg Tablet is an anticancer medicine used to treat Non-small cell lung cancer with certain mutations of EGFR in adults.

How does Geftinat 250mg Tablet(Gefitinib 250mg) work?

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Geftinat 250mg Tablet is work by targeting and blocking the action of specific receptor to slow down the spread of cancer.

Is it safe to drive after taking Geftinat 250mg Tablet?

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It is not safe to drive after taking this medicine as it can cause dizziness or lack of concentration as are common symptoms.

is it safe to take Geftinat 250mg Tablet(Gefitinib 250mg) if a patient has liver related condition?

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Yes Liver related patient can take Geftinat 250mg after consulting the doctor.

Marketer Details

Natco Pharma

Rating and Reviews

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Author Details

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Written By:

Nonish Sharma

I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More


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Reviewed By:

Vaibhav Shakya

Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More

Last Updated: 07 Sept 2026 | 04:13 pm (IST)

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