Enasinib 50mg Tablet (Enasidenib)
Prescription RequiredManufactured By
Everest
Pack Of
30
Salt Composition
Enasidenib
Storage
Keep in cold place
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ALL SUBSTITUTES
Idhifa 50mg Tablet
Overview
Enasinib 50mg Tablet is a prescription-based anticancer medicine used in the treatment of acute myeloid leukemia in adults with an IDH2 mutation. The active ingredient of Enasinib is Enasidenib which belongs to the drug class of socitrate dehydrongenase-2 (IDH2) inhibitor.
It works by inhibiting the function of mutated IDH2 enzyme to control the growth of abnormal cancer cells. Enasidenib Tablet is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
Indication
Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer
Side Effects
The human body shows undesired symptoms after taking Enasidenib 50mg Tablet (Enasinib). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Some of the common side effects of Enasinib tablets are mentioned below:
● Fever
● Cough
● Nausea
● Vomiting
● Diarrhea
● Jaundice
● Bone pain
● Loss of appetite
● Trouble breathing
● Rapid weight gain
● Swelling in your arms, legs, underarms, groin, or neck
How To Use
Enasidenib 50mg Tablet (Enasinib) is a prescription-based anticancer drug that should be administered orally. It is advised to take this tablet after consulting your healthcare expert.
This tablet should be swallowed as a whole with water. Don't crush, chew, or break it. It can be taken with or without food. Never skip a dose or double dose.
Reference
● Dugan, J., & Pollyea, D. (2018). Enasidenib for the treatment of acute myeloid leukemia. Expert review of clinical pharmacology, 11(8), 755-760.
● Stein, E. M., Fathi, A. T., DiNardo, C. D., Pollyea, D. A., Roboz, G. J., Collins, R., ... & Kantarjian, H. M. (2020). Enasidenib in patients with mutant IDH2 myelodysplastic syndromes: a phase 1 subgroup analysis of the multicentre, AG221-C-001 trial. The Lancet Haematology, 7(4), e309-e319.
● Pollyea, D. A., Tallman, M. S., de Botton, S., Kantarjian, H. M., Collins, R., Stein, A. S., ... & Stein, E. M. (2019). Enasidenib, an inhibitor of mutant IDH2 proteins, induces durable remissions in older patients with newly diagnosed acute myeloid leukemia. Leukemia, 33(11), 2575.
● Stein, E. M., DiNardo, C. D., Pollyea, D. A., Fathi, A. T., Roboz, G. J., Altman, J. K., ... & Tallman, M. S. (2017). Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia. Blood, The Journal of the American Society of Hematology, 130(6), 722-731.
● Kim, E. S. (2017). Enasidenib: first global approval. Drugs, 77(15), 1705-1711.
Safety Advice
- ● Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Enasinib 50mg Tablet (Enasidenib). It is advised to consult your doctor for further information.
- ● Pregnancy: Enasinib 50mg Tablet (Enasidenib) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- ● Breastfeeding: Enasidenib 50mg Tablet (Enasinib) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- ● Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Enasinib 50mg Tablet (Enasidenib).
- ● Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Enasinib 50mg Tablet (Enasidenib).
- ● Liver: Inform your doctor before starting Enasidenib 50mg Tablet (Enasinib) if you have liver disease to avoid any serious side effects.
FAQs
Why do doctors prescribe Enasinib 50mg Tablet (Enasidenib)?
This medicine is given to adults diagnosed with acute myeloid leukemia with an IDH2 mutation.
What is the right way of taking the Enasidenib 50mg Tablet (Enasinib)?
Enasinib (Enasidenib) is taken orally with or without food as per the doctor's advice. It is consumed at the same time each day for better results. It is recommended not to crush, chew, or split the tablet, take it as a whole.
What are the commonly observed side effects of Enasiniba 50mg Tablet (Enasidenib)?
The most common side effects of this medicine include Diarrhea, Headache, Tiredness, Dry mouth, Constipation, Stomach pain, and difficulty breathing. It is advised to go for regular liver function tests to examine the liver function.
Who should avoid taking Enasinib 50mg Tablet (Enasidenib)?
People diagnosed with severe liver and kidney disorders are advised to consult their healthcare professionals before taking this medicine.
Can the Enasidenib 50mg Tablet (Enasinib) be given in combination therapy with other medications?
No, there are chances that Enasinib may interact with certain drugs. It is crucial to inform your healthcare expert if you're already taking any medication.
Marketer Details
Everest
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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