Avastin 400mg Injection (Bevacizumab)

Avastin 400mg injection is a prescription-based targeted anticancer medicine used in the treatment of breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, and colorectal cancer. The active ingredient of Avastin is bevacizumab, which belongs to the drug class of vascular endothelial growth factor (VEGF) inhibitors. It works by acting against protein known as Vascular Endothelial Growth Factors (VEGF) to control the growth and spread of the cancer cells. Bevacizumab injection is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.

The injection is administered as an intravenous infusion by a qualified doctor in a hospital or clinical setting. The doctor determines the dosage of the Bevacizumab 400mg injection according to the type of cancer, treatment regimen, age, and overall health of the patient. It should not be self-administered. Patients are advised not to change the dosage and timings prescribed by the doctors because it can cause severe side effects.

Common side effects include high blood pressure, tiredness, weakness, headache, loss of appetite, diarrhea, nausea, mouth sores, and joint or muscle pain. A few patients can undergo severe side effects, including severe bleeding, blood clots, gastrointestinal perforation, impaired wound healing, or kidney problems. Most of the Bevacizumab 400mg injection side effects can leave when the body adapts to the medicine. However, report to your doctor if you experience serious side effects.

The medicine can impair wound healing, so it may need to be stopped before or after surgery, and pregnant patients or breastfeeding mothers should consult with their doctor before the treatment. Patients must list all medicines, supplements, and herbal products that they are taking. The Bevacizumab 400mg injection must be used under medical oversight or medical supervision only. Attend regular tests and follow-ups to monitor the medicine response and reduce side effects. Before making any adjustments, changing the dose, or stopping the treatment, consult with your doctor to maximize the benefit.

Colorectal cancer

The human body shows undesired symptoms after taking Bevacizumab 400mg injection (Avastin). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.

Avastin 400mg injection (Bevacizumab) is a prescription-based anticancer drug. It is advised to take this injection after consulting your healthcare expert. This medicine should be given intravenously by an experienced nurse or doctor. Please do not self-administer.

● Lauro, S., Onesti, C. E., Righini, R., & Marchetti, P. (2014). The use of bevacizumab in non-small cell lung cancer: an update. Anticancer research, 34(4), 1537-1545.
● Burger, R. A., Brady, M. F., Bookman, M. A., Fleming, G. F., Monk, B. J., Huang, H., ... & Liang, S. X. (2011). Incorporation of bevacizumab in the primary treatment of ovarian cancer. New England Journal of Medicine, 365(26), 2473-2483.
● Keating, G. M. (2014). Bevacizumab: a review of its use in advanced cancer. Drugs, 74(16), 1891-1925.
● Ferrara, N., Hillan, K. J., Gerber, H. P., & Novotny, W. (2004). Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nature reviews Drug discovery, 3(5), 391-400.
● Kazazi-Hyseni, F., Beijnen, J. H., & Schellens, J. H. (2010). Bevacizumab. The oncologist, 15(8), 819