Aprepit 125mg Capsule (Aprepitant)
Prescription RequiredManufactured By
Cipla
Pack Of
3
Salt Composition
Aprepitant
Storage
Keep in cold place
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Overview
Aprepit 125mg Capsule is an antimetic drug that is used to prevent nausea and vomiting caused due to chemotherapy during cancer treatment. It contains Aprepitant 125mg that is a selective high affinity antagonist of human substance P/ neurokinin 1 (NK1) receptors. Aprepitant blocks the NK1 receptors, preventing substance P- a neuropeptide that induces signals from binding to these receptors in brain , thus inhibiting the vomiting reflex.
Quick Product Facts
| Field | Publication wording |
|---|---|
| Brand | aprepit |
| Generic / Active Ingredient | Aprepitant |
| Strength | 125 |
| Dosage Form | Capsule |
| Manufacturer / Marketer | cipla |
| Pack Size | 3 |
| Prescription Required | Yes |
| Therapeutic Categories | Cancer Medicines |
| Uses | Nausea and Vomiting |
Uses and Indications
Chemotherapy, Nausea and Vomiting
Side Effects of Aprepit 125mg Capsule
Aprepit 125mg Capsule(Aprepitant 125mg) may cause several side effects, mostly ,mild to moderate. Patients are advised to inform healthcare providers immediately, if they experience some serious side effects or prolonged symptoms.
Common Side Effects of Aprepit 125mg Capsule
● Tiredness
● Constipation
● Headache
● Dizziness
● Indigestion
● Heartburn
● Loss of Appetite
● Abdominal Pain
Less common Side Effects of Aprepit 125mg Capsule
● Signs of Infection
● Confusion
● Changes in Mental Status
● Chest Pain
● Palpitations
● Urinay Problem
● Pain during Urination
Aprepit 125mg Capsule Dosage and How To Take It
For adults and children over the age of twelve, the standard dosage of Aprepit 125mg Capsule(Aprepitant 125mg) taken orally(typically one capsule) one hour before to the first day of chemotherapy. After chemotherapy, use 80 mg once daily in the morning on days two and three.
Swallow the entire tablet for consumption. To preserve the effectiveness of the capsules, do not break, crush, chew, or bite them. Depending on the particular treatment and doctor's orders, the precise length and dosage may change. Always adhere to the dose recommendations provided by your doctor.
Safety Advice for Aprepit 125mg Capsule
- 1. It is advisable not to consume alcohol while taking Aprepit 125mg Capsule(Aprepitant 125mg) medicine as it can decrease its efficacy. It is advised to consult your doctor for further information.
- 2. Aprepit 125mg Capsule is considered unsafe for pregnancy due to fetal harm. Please consult your doctor in such condition.
- 3. Breast Feeding is also not advisable during the course of Aprepit 125mg Capsule(Aprepitant 125mg). Consult your Doctor for more information.
- 4. It is advisable not to drive or operate any heavy machinery, as you may feel dizzy after taking Aprepit 125mg Capsule.
- 5. Share your medical history related to kidney cancer with your doctor before taking Aprepit 125mg Capsule(Aprepitant 125mg).
- 6. Notify your doctor about any liver disease or infection before starting Aprepit 125mg Capsule course.
FAQs About Aprepit 125mg Capsule
What is the use of Aprepit 125mg Capsule(Aprepitant 125mg)?
The major use of Aprepit 125mg Capsule is to prevent nausea and vomiting caused due to chemotherapy in cancer treatment.
Can Aprepit 125mg Capsule cause Liver Problems?
Yes, Aprepit 125mg Capsule(Aprepitant 125mg) can cause mild liver problems. But, it can lead to severe effects, if not addressed timely with other alternative.
Can Aprepit 125mg Capsule be given with other medication?
Yes, Aprepit 125mg Capsule can be given in combination with other medicine based on doctor's assessment about your disease and its stage.
Is Pregnancy and Breastfeeding safe during Aprepit 125mg Capsule(Aprepitant 125mg) course?
No, its not advice to be pregnant or breastfeed during Aprepit 125mg Capsule course.
How Aprepit 125mg Capsule works?
Aprepit 125mg Capsule(Aprepitant 125mg) contains Aprepitant that blocks the NK1 receptors in the central nervous system thus, blocking the emetic signals triggered by substance P to cause symptoms.
References
● Curran, M. P., & Robinson, D. M. (2009). Aprepitant: a review of its use in the prevention of nausea and vomiting. Drugs, 69(13), 1853-1878.
● Duval, A., & Dubertret, L. (2009). Aprepitant as an antipruritic agent?. New England Journal of Medicine, 361(14), 1415-1416.
● Dando, T. M., & Perry, C. M. (2004). Aprepitant: a review of its use in the prevention of chemotherapy-induced nausea and vomiting. Drugs, 64(7), 777-794.
● Padilla, A., & Habib, A. S. (2023). A pharmacological overview of aprepitant for the prevention of postoperative nausea and vomiting. Expert Review of Clinical Pharmacology, 16(6), 491-505.
Marketer Details
Cipla
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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