Apremac Capsule (Aprepitant)
Prescription RequiredManufactured By
Admac life science
Pack Of
3
Salt Composition
Aprepitant
Storage
Keep in cold place
ALL SUBSTITUTES
Aprepit 125mg Capsule
Aprineon 125mg/80mg Capsule
Aprecap Capsule
Apretero Capsule
Aprepit 125mg/80mg Capsule
Prepit Capsule
Overview
Apremac Capsule is an antimetic medication that is used to prevent nausea and vomiting caused by the chemotherapy and cancer treatments. It contains aprepitant salt that works by blocking the action of substance P, a natural substance in the brain that triggers the nausea and vommiting symptoms. Aprepitant blocks the NK1 receptors in the central nervous system thus, blocking the the emetic signals triggered by substance P.
Quick Product Facts
| Field | Publication wording |
|---|---|
| Brand | apremac |
| Generic / Active Ingredient | Aprepitant |
| Strength | 125 |
| Dosage Form | Capsule |
| Manufacturer / Marketer | admac life science |
| Pack Size | 3 |
| Prescription Required | Yes |
| Therapeutic Categories | Cancer Medicines, Rheumatoid Arthritis |
| Uses | Nausea and Vomiting |
Uses and Indications
Chemotherapy, Nausea and Vomiting
Side Effects of Apremac Capsule
Like any other chemical-based medication, Apremac Capsule(Aprepitant) side effects also ranges from mild to serious. Patients are advised to seek immediate medical attention if they experience any signs of an allergic reaction, severe problems or prolonged symptoms.
Common Side Effects of Apremac Capsule
● Constipation
● Headache
● Indigestion
● Heartburn
● Tiredness
● Loss of Apetite
● Hiccups
● Dizziness
● Diarrhea
● Increased Liver Enzymes
Serious Side Effects of Apremac Capsule
● Severe Allergic Reaction
● Unusual Bleeding
● Brusing
● Signs of Infection
● Blistering
● Severe Skin Reactions
Apremac Capsule Dosage and How To Take It
Typical dosage of Apremac Capsule(Aprepitant) for adults and children above 12 years is 125mg (usually one capsule) orally 1 hour before chemotherapy on day 1. Take 80mg once daily on the morning of day 2 and day 3 after chemotherapy.
Swallow the whole tablet as it is. Avoid breaking, crushing, chewing or biting of capsules to maintain its efficacy. The exact duration as well as the dose may vary depending on the specific chemotherapy and physician instructions. Always follow the physician's specific dosage instructions.
Safety Advice for Apremac Capsule
- 1. It is advisable not to consume alcohol while taking Apremac Capsule(Aprepitant) medicine as it can decrease its efficacy. It is advised to consult your doctor for further information.
- 2. Apremac Capsule is considered unsafe for pregnancy due to fetal harm. Please consult your doctor in such condition.
- 3. Breast Feeding is also not advisable during the course of Apremac Capsule(Aprepitant). Consult your Doctor for more information.
- 4. It is advisable not to drive or operate any heavy machinery, as you may feel dizzy after taking Apremac Capsule.
- 5. Share your medical history related to kidney cancer with your doctor before taking Apremac Capsule(Aprepitant).
- 6. Notify your doctor about any liver disease or infection before starting Apremac Capsule course.
FAQs About Apremac Capsule
What is the use of Apremac Capsule(Aprepitant Capsule)?
The major use of Apremac Capsule is to prevent nausea and vomiting caused due to chemotherapy in cancer treatment.
Can Apremac Capsule cause Liver Problems?
Yes, Apremac Capsule can cause mild liver problems. But, it can lead to severe effects, if not addressed timely with other alternative.
Can Apremac Capsule be given with other medication?
Yes, Apremac Capsule(Aprepitant) can be given in combination with other medicine based on doctor's assessment about your disease and its stage.
Is Pregnancy and Breastfeeding safe during Apremac Capsule course?
No, its not advice to be pregnant or breastfeed during Apremac Capsule(Aprepitant) course.
How Apremac Capsule works?
Apremac Capsule contains Aprepitant that blocks the NK1 receptors in the central nervous system thus, blocking the emetic signals triggered by substance P to cause symptoms.
References
● Curran, M. P., & Robinson, D. M. (2009). Aprepitant: a review of its use in the prevention of nausea and vomiting. Drugs, 69(13), 1853-1878.
● Duval, A., & Dubertret, L. (2009). Aprepitant as an antipruritic agent?. New England Journal of Medicine, 361(14), 1415-1416.
● Dando, T. M., & Perry, C. M. (2004). Aprepitant: a review of its use in the prevention of chemotherapy-induced nausea and vomiting. Drugs, 64(7), 777-794.
● Padilla, A., & Habib, A. S. (2023). A pharmacological overview of aprepitant for the prevention of postoperative nausea and vomiting. Expert Review of Clinical Pharmacology, 16(6), 491-505.
Marketer Details
Admac life science
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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