Abirakast 250mg Tablet (Abiraterone Acetate)

The Abirakast 250mg Tablet is a prescription anticancer medication that treats advanced prostate cancer in males. The abiraterone acetate belongs to the class of androgen biosynthesis inhibitors. It reduces testosterone levels and slows or stops the growth of cancer by inhibiting the CYP17 enzyme. This enzyme is responsible for androgen production in the testes and adrenal glands. Therefore, after lowering the levels of androgen, Abirakast targets the growth of prostate cancer and also prevents its division.

It is prescribed by doctors for both high-risk castration-sensitive prostate cancer that still responds to hormone suppression and castration-resistant prostate cancer that no longer responds to hormone therapy or surgery. However, the dosage and timings of abiraterone acetate 250mg tablet treatment depend on the type and stage of prostate cancer. Doctors recommend opting for regular medical monitoring and testing of liver function, blood pressure, and potassium levels.

The medicine must be taken on an empty stomach and taken exactly as prescribed by the doctor. Ensure to consume the tablet as a whole with water. Do not crush, chew, or break the tablet until your doctor advises you to do it. Common side effects of abiraterone acetate 250mg tablets that may arise are diarrhea, vomiting, headaches, joint pain, hypertension, water retention, and tiredness. Patients must inform their doctor about past medicines, disorders, liver abnormalities and heart conditions before taking or starting the treatment.

Patients must list all medicines, supplements, and herbal products that they are taking. The abiraterone acetate 250mg tablet must be used under medical oversight or medical supervision only. Attend regular tests and follow-ups to monitor the medicine response and reduce side effects. Before making any adjustments, changing the dose, or stopping the treatment, consult with your doctor to maximize the benefit.

Prostate Cancer

The human body reacts differently to Abirakast 250mg Tablet (Abiraterone Acetate 250mg). Response or undesired symptoms vary from individual to individual. Usually, they disappear with time as the body adjusts to the medicine.

These side effects don't need special medical attention. However, if the symptoms don't disappear with time or you have severe side effects, then consult your doctor immediately.​

Some of the common side effects of Abirakast 250mg:
● Edema (swelling)
● Vomiting
● Decreased potassium level in blood
● Fatigue
● Anemia (low number of red blood cells)
● Urinary tract infection
● Diarrhea
● High blood pressure
● Cough
● Joint swelling
● Nausea
● Hot flashes
● Headache
● Increased glucose level in blood

Take the Abirakast 250mg Tablet (Abiraterone Acetate 250mg) in the dosage as prescribed by the doctor. Dosage and the duration were determined as per the patients health condition. This tablet should be swallowed as a whole with water. Don't crush, chew, or break the tablet. It should be taken on an empty stomach. Never skip a dose or double dose.

● Stappaerts, J., Geboers, S., Snoeys, J., Brouwers, J., Tack, J., Annaert, P., & Augustijns, P. (2015). Rapid conversion of the ester prodrug abiraterone acetate results in intestinal supersaturation and enhanced absorption of abiraterone: in vitro, rat in situ and human in vivo studies. European Journal of Pharmaceutics and Biopharmaceutics, 90, 1-7.
● Acharya, M., Bernard, A., Gonzalez, M., Jiao, J., De Vries, R., & Tran, N. (2012). Open-label, phase I, pharmacokinetic studies of abiraterone acetate in healthy men. Cancer chemotherapy and pharmacology, 69(6), 1583-1590.
● Yang, L. P. (2011). Abiraterone acetate: in metastatic castration-resistant prostate cancer. Drugs, 71(15), 2067-2077.
● Akbel, E. (2024). Development, validation, and greenness assessment of eco-friendly analytical methods for the determination of abiraterone acetate in pure form and pharmaceutical formulations. Separations, 11(10), 290.
● Auchus, R. J., Buschur, E. O., Chang, A. Y., Hammer, G. D., Ramm, C., Madrigal, D., ... & Yu, M. K. (2014). Abiraterone acetate to lower androgens in women with classic 21-hydroxylase deficiency. The Journal of Clinical Endocrinology & Metabolism, 99(8), 2763-2770