Ts-One 20mg Capsule (Tegafur Gimeracil Oteracil Potassium)
Prescription RequiredManufactured By
Taiho
Pack Of
56
Salt Composition
Tegafur Gimeracil Oteracil Potassium
Storage
Keep in cold place
Overview
TS One 20mg capsule is a prescription-based anticancer medicine used in the treatment of gastric cancer, colorectal, head and neck, non-small cell lung cancer, breast, pancreatic, biliary tract cancer. The active ingredient of the TS One is Tegafur, Gimeracil, Oteracil Potassium which belongs to the drug class of fluoropyrimidines and thymidylate synthase inhibitors.
After being taken into the body, it is metabolized to become 5-fluorouracil (5-FU). 5-FU is an anticancer agent that prevents the formation of enzymes needed for the synthesis of DNA and RNA. This makes it impossible for the cancer cells to divide or multiply.
Tegafur Gimeracil Oteracil Potassium capsule is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
Quick Product Facts
| Field | Publication wording |
|---|---|
| Brand | ts one |
| Generic / Active Ingredient | Tegafur Gimeracil Oteracil Potassium |
| Strength | 20 |
| Dosage Form | Capsule |
| Manufacturer / Marketer | Taiho |
| Pack Size | 56 |
| Prescription Required | Yes |
| Therapeutic Categories | Cancer Medicines |
Uses and Indications
Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer
Side Effects of Ts-One 20mg Capsule
The human body shows undesired symptoms after taking TS One 20mg capsule (Tegafur). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Common or Clinically Frequent Side Effects
- Some of the common side effects of TS One capsule are mentioned below:
- ● Fever
- ● Chills
- ● Nausea
- ● Vomiting
- ● Diarrhea
- ● Headache
- ● Tiredness
- ● Sore throat
- ● Dehydration
- ● Lack of energy
- ● Abdominal pain
- ● Speech disorder
- ● Unusual bleeding
- ● Irregular heartbeat
- ● Sensory disturbance
Ts-One 20mg Capsule Dosage and How To Take It
Take Tegafur Gimeracil 20mg capsule (TS One) in dosage as prescribed by the doctor. Dosage and the duration determined as per stage & type of cancer and the patients’ health condition. This capsule should be swallowed as a whole with water. Don't crush, chew, or break the capsule. It should be taken with food. Never skip a dose or double dose.
Safety Advice for Ts-One 20mg Capsule
- ● Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking TS One 20mg capsule (Tegafur). It is advised to consult your doctor for further information.
- ● Pregnancy: TS One 20mg capsule (Tegafur) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- ● Breastfeeding: Tegafur Gimeracil 20mg capsule (TS One) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- ● Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking TS One 20mg capsule (Tegafur).
- ● Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Tegafur 20mg capsule (TS One).
- ● Liver: Inform your doctor before starting TS One 20mg capsule (Tegafur) if you have liver disease to avoid any serious side effects.
FAQs About Ts-One 20mg Capsule
Why do doctors prescribe TS One 20mg capsule (Tegafur)?
This medicine is given to adults diagnosed with gastric cancer, colorectal, head and neck, non-small cell lung cancer, breast, pancreatic, biliary tract cancer.
What is the right way of taking the Tegafur Gimeracil 20mg capsule (TS One)?
Tegafur Gimeracil 20mg capsule is taken orally with or without food as per the doctor's advice. It is consumed at the same time each day for better results. It is recommended not to crush, chew, or split the capsules; take them as a whole.
What are the commonly observed side effects of TS One 20mg capsule (Tegafur)?
The most common side effects of this medicine include Diarrhea, Headache, Tiredness, Mouth sores, Muscle or joint pain, Stomach pain, and difficulty breathing. It is advised to go for regular liver function tests to examine the liver function.
Who should avoid taking TS One 20mg capsule (Tegafur)?
People diagnosed with severe liver and kidney disorders are advised to consult their healthcare professionals before taking this medicine.
Can the Tegafur 20mg capsule (TS One) be given in combination therapy with other medications?
No, there are chances that Tegafur may interact with certain drugs. It is crucial to inform your healthcare expert if you're already taking any medication.
References
● Wellington, K., & Goa, K. L. (2001). Oral tegafur/uracil. Drugs & aging, 18(12), 935-948.
● Li, Z., Li, P., Wu, S., Zhang, M., Zhang, F., Zheng, L., & Su, L. (2026). Tolerance and response of afatinib combined with tegafur in patients with advanced biliary tract cancer after failure of gemcitabine-based systemic therapy. Discover Oncology.
● Pazdur, R., Lassere, Y., Rhodes, V., Ajani, J. A., Sugarman, S. M., Patt, Y. Z., ... & Bready, B. (1994). Phase II trial of uracil and tegafur plus oral leucovorin: an effective oral regimen in the treatment of metastatic colorectal carcinoma. Journal of clinical oncology, 12(11), 2296-2300.
● Kajanti, M. J., Pyrhönen, S. O., & Maiche, A. G. (1993). Oral tegafur in the treatment of metastatic breast cancer: a phase II study. European Journal of Cancer, 29(6), 863-866.
● Kobayakawa, M., & Kojima, Y. (2011). Tegafur/gimeracil/oteracil (S-1) approved for the treatment of advanced gastric cancer in adults when given in combination with cisplatin: a review comparing it with other fluoropyrimidine-based therapies. OncoTargets and therapy, 193-201.
Marketer Details
Taiho
Author Details
Written By:
Nonish Sharma
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Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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