Selcaxen 40mg Capsule (Selpercatinib)
Prescription RequiredManufactured By
Everest
Pack Of
30
Salt Composition
Selpercatinib
Storage
Keep in cold place
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Retevmo 40mg Capsule
Overview
Selcaxen 40mg Capsule is a prescription-based anticancer medicine used in the treatment of certain type of cancers including Non-Small Cell Lung Cancer (NSCLC), thyroid cancer, medullary thyroid cancer, and certain other solid tumors.
The active ingredient of the Selcaxen is Selpercatinib which belongs to the drug class of kinase inhibitors. The growth of cancer cells is uncontrollable and abnormal in the human body. It is difficult to diagnose cancer in the early stages as there are no
Indication
Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer
Side Effects
The human body shows undesired symptoms after taking Selpercatinib 40mg Capsule (Selcaxen). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Some of the common side effects of Selcaxen are mentioned below:
● Rash
● Nausea
● Diarrhea
● Headache
● Tiredness
● Dry mouth
● Constipation
● Stomach pain
● Fluid retention
● High blood pressure
● Decreased white blood cells
● Changes in liver function tests
● Low levels of sodium and calcium
How To Use
Selpercatinib 40mg Capsule (Selcaxen) is a prescription-based anticancer drug that should be administered orally. It is advised to take this Capsule after consulting your healthcare expert. This capsule should be swallowed as a whole with water. Don't crush, chew, or break it. It can be taken with or without food. Never skip a dose or double dose.
Reference
● Duke, E. S., Bradford, D., Marcovitz, M., Amatya, A. K., Mishra-Kalyani, P. S., Nguyen, E., ... & Singh, H. (2023). FDA approval summary: selpercatinib for the treatment of advanced RET fusion-positive solid tumors. Clinical cancer research, 29(18), 3573-3578.
● Subbiah, V., Wolf, J., Konda, B., Kang, H., Spira, A., Weiss, J., ... & Drilon, A. (2022). Tumour-agnostic efficacy and safety of selpercatinib in patients with RET fusion-positive solid tumours other than lung or thyroid tumours (LIBRETTO-001): a phase 1/2, open-label, basket trial. The Lancet Oncology, 23(10), 1261-1273.
● Wirth, L. J., Sherman, E., Robinson, B., Solomon, B., Kang, H., Lorch, J., ... & Cabanillas, M. E. (2020). Efficacy of selpercatinib in RET-altered thyroid cancers. New England Journal of Medicine, 383(9), 825-835.
● Zhou, C., Solomon, B., Loong, H. H., Park, K., Pérol, M., Arriola, E., ... & Goto, K. (2023). First-line selpercatinib or chemotherapy and pembrolizumab in RET fusion–positive NSCLC. New England Journal of Medicine, 389(20), 1839-1850.
● Markham, A. (2020). Selpercatinib: first approval. Drugs, 80(11), 1119-1124
Safety Advice
- ● Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Selcaxen 40mg Capsule (Selpercatinib). It is advised to consult your doctor for further information.
- ● Pregnancy: Selpercatinib 40mg Capsule (Selcaxen) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- ● Breastfeeding: Selcaxen 40mg Capsules (Selpercatinib) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- ● Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Selcaxen 40mg Capsule (Selpercatinib).
- ● Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Selpercatinib 40mg Capsule (Selcaxen).
- ● Liver: Inform your doctor before starting Selcaxen 40mg Capsule (Selpercatinib) if you have liver disease to avoid any serious side effects.
FAQs
Why do doctors prescribe Selcaxen 40mg Capsule (Selpercatinib)?
This medicine is given to people diagnosed with non-small cell lung cancer (NSCLC), thyroid cancer, medullary thyroid cancer, and certain other solid tumors.
What is the right way of taking the Selpercatinib 40mg Capsule (Selcaxen)?
Selcaxen is taken orally with or without food as per the doctor's advice. It is consumed at the same time each day for better results. It is recommended not to crush, chew, or split the Capsule, take it as a whole.
What are the commonly observed side effects of Selcaxen 40mg Capsule (Selpercatinib)?
The most common side effects of this medicine include Diarrhea, Headache, Tiredness, Dry mouth, Constipation, Stomach pain, and Fluid retention. It is advised to go for regular liver function tests to examine the liver function.
Who should avoid taking Selcaxen Capsule (Selpercatinib)?
People diagnosed with severe liver and kidney disorders are advised to consult their healthcare professionals before taking this medicine.
Can the Selpercatinib 40mg Capsule (Selcaxen) be given in combination therapy with other medications?
No, there are chances that Selpercatinib may interact with certain drugs. It is crucial to inform your healthcare expert if you're already taking any medication.
Marketer Details
Everest
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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