Niranib 100mg Capsule (Niraparib)
Prescription RequiredManufactured By
Everest
Pack Of
30
Salt Composition
Niraparib
Storage
Keep in cold place
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ALL SUBSTITUTES
Zejula 100mg Capsule
Overview
Niranib 100mg Capsule is a prescription-based anticancer medicine used in the treatment of advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer.
The active ingredient of the Niranib is Niraparib which belongs to the drug class of Poly (ADP-ribose) polymerase (PARP) inhibitors.
It works by blocking the action of PARP enzymes that repair damaged DNA in cancer cells result in this medicine prevents the cancer cells from repairing themselves which leads to their death. Niraparib Capsule is given as a monotherapy treatment.
Indication
Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer
Side Effects
The human body shows undesired symptoms after taking Niranib 100mg Capsule (Niraparib). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Some of the common side effects of Niranib Capsule are mentioned below:
● Nausea and vomiting
● Rash
● Diarrhea
● Dizziness
● Headache
● Muscle pain
● Stomach pain
● Constipation
● Bladder infection
● Decreased appetite
● High blood pressure
● Changes in your urine color
● Tiredness and trouble sleeping
● Lung problems, such as shortness of breath and cough
● Changes in blood levels including red blood cells, white blood cells, and platelets
How To Use
Niranib 100mg Capsule (Niraparib) is a prescription-based anticancer drug that should be administered orally. Niranib is taken orally with or without food as per the doctor's advice.
It is consumed at the same time each day for better results. It is recommended not to crush, chew, or split the capsule, take it as a whole.
Reference
● Liu, M. C., Sutedja, J., & Tewari, K. S. (2021). Niraparib in the maintenance treatment of advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer: safety and efficacy. Expert review of anticancer therapy, 21(5), 475-480.
● Kerliu, L., Myruski, S., Bhatti, A., Soni, P., Petrosius, P., Pervanas, H. C., & Horton, E. R. (2020). Niraparib for the treatment of recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer. Annals of Pharmacotherapy, 54(10), 1010-1015.
● González-Martín, A., Pothuri, B., Vergote, I., DePont Christensen, R., Graybill, W., Mirza, M. R., ... & Monk, B. J. (2019). Niraparib in patients with newly diagnosed advanced ovarian cancer. New England Journal of Medicine, 381(25), 2391-2402.
● Smith, M. R., Scher, H. I., Sandhu, S., Efstathiou, E., Lara, P. N., Yu, E. Y., ... & Moon, H. (2022). Niraparib in patients with metastatic castration-resistant prostate cancer and DNA repair gene defects (GALAHAD): a multicentre, open-label, phase 2 trial. The Lancet Oncology, 23(3), 362-373.
● Ison, G., Howie, L. J., Amiri-Kordestani, L., Zhang, L., Tang, S., Sridhara, R., ... & Pazdur, R. (2018). FDA approval summary: niraparib for the maintenance treatment of patients with recurrent ovarian cancer in response to platinum-based chemotherapy. Clinical Cancer Research, 24(17), 4066-4071.
● Scott, L. J. (2017). Niraparib: first global approval. Drugs, 77(9), 1029-1034.
Safety Advice
- ● Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Niranib 100mg Capsule (Niraparib). It is advised to consult your doctor for further information.
- ● Pregnancy: Niranib 100mg Capsule (Niraparib) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- ● Breastfeeding: Niranib 100mg Capsule (Niraparib) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- ● Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Niranib 100mg Capsule (Niraparib).
- ● Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Niranib 100mg Capsule (Niraparib).
- ● Liver: Inform your doctor before starting Niranib 100mg Capsule (Niraparib) if you have liver disease to avoid any serious side effects
FAQs
Why do doctors prescribe Niranib 100mg Capsule (Niraparib)?
This medicine is given to patients diagnosed with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer.
What is the right way of taking the Niranib 100mg Capsule (Niraparib)?
Niranib 100mg Capsule is taken orally with or without food as per the doctor's advice. It is consumed at the same time each day for better results. It is recommended not to crush, chew, or split the capsule, take it as a whole.
What are the commonly observed side effects of Niranib 100mg Capsule?
The most common side effects of this medicine include Diarrhea, Headache, Tiredness, Mouth sores, Muscle or joint pain, Stomach pain, and difficulty breathing. It is advised to go for regular liver function tests to examine it.
Who should avoid taking Niranib 100mg Capsule (Niraparib)?
People diagnosed with severe liver and kidney disorders are advised to consult their healthcare professionals before taking this medicine.
Can the Niranib 100mg Capsule (Niraparib) be given in combination therapy with other medications?
No, there are chances that Niranib may interact with certain drugs. It is crucial to inform your healthcare expert if you're already taking any medication.
Marketer Details
Everest
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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