Mekinist 2mg Tablet (Trametinib)
Prescription RequiredManufactured By
Novartis
Pack Of
30
Salt Composition
Trametinib
Storage
Keep in cold place
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Up to 60% Discounts
ALL SUBSTITUTES
Mekinist 0.5mg Injection
Overview
Mekinist 2mg Tablet is a prescription-based anticancer medicine used in the treatment of melanoma, non-small cell lung cancer,thyroid, and Metastatic solid tumours. The active ingredient of the Mekinist is Trametinib which belongs to the drug class of Protein Kinase Inhibitors.
It works on the principle of inhibiting the action of an abnormal protein which is responsible for giving signals to cancerous cells to divide and grow. Trametinib is prescribed when there is metastasis of cancer, surgery cannot be done, or in order to prevent recurrence of cancer after surgery.
Indication
Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer
Side Effects
The human body shows undesired symptoms after taking Mekinist 2mg Tablet (Trametinib). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Common Side Effects
- Some of the common side effects of Trametinib Tablet are mentioned below:
- ● Fever
- ● Fatigue
- ● Diarrhea
- ● Bleeding
- ● Headache
- ● Back pain
- ● Joint pain
- ● Dehydration
- ● Constipation
- ● Muscles pain
- ● Loss in appetite
- ● Faster heart rate
- ● Skin inflammation
- ● Nausea and vomiting
- ● Low blood cell count
- ● Difficulty in breathing
Serious Side Effects
- ● Liver infection
- ● tear in the stomach or intestine
- ● Low level of white blood cells
- ● Inflammation in nasal and throat
How To Use
Trametinib 2mg Tablet (Mekinist) is a prescription-based anticancer drug that should be administered orally. It is advised to take this tablet after consulting your healthcare expert. Take this tablet on an empty stomach for better results. Before starting this medicine, please inform your doctor about your medical history.
If you experience any signs and symptoms while taking this medication that are not manageable, do not ignore those symptoms because they may lead to a higher risk.
Missed Doses
Instructions if you miss a dose
Reference
● Wright, C. J., & McCormack, P. L. (2013). Trametinib: first global approval. Drugs, 73(11), 1245-1254.
● Salama, A. K., & Kim, K. B. (2013). Trametinib (GSK1120212) in the treatment of melanoma. Expert opinion on pharmacotherapy, 14(5), 619-627.
● Thota, R., Johnson, D. B., & Sosman, J. A. (2015). Trametinib in the treatment of melanoma. Expert opinion on biological therapy, 15(5), 735-747.
● Lugowska, I., Koseła-Paterczyk, H., Kozak, K., & Rutkowski, P. (2015). Trametinib: a MEK inhibitor for management of metastatic melanoma. OncoTargets and therapy, 2251-2259.
● Falchook, G. S., Lewis, K. D., Infante, J. R., Gordon, M. S., Vogelzang, N. J., DeMarini, D. J., ... & Fecher, L. A. (2012). Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial. The lancet oncology, 13(8), 782-789
Safety Advice
- ● Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Trametinib 2mg Tablet (Mekinist). It is advised to consult your doctor for further information.
- ● Pregnancy: Mekinist 2mg Tablet (Trametinib) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- ● Breastfeeding: Trametinib 2mg Tablet (Mekinist) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- ● Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Mekinist 2mg Tablet (Trametinib).
- ● Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Trametinib 2mg Tablet (Mekinist).
- ● Liver: Inform your doctor before starting Mekinist 2mg Tablet (Trametinib) if you have liver disease to avoid any serious side effects
FAQs
What is the best way to take a Trametinib 2mg Tablet (Mekinist)?
Your doctor will decide the dosage for taking the drug. You must take it with or without food as per prescription. Do not chew, crush, or break the Tablet, just take it whole with water.
Can Mekinist Tablet (Trametinib) be taken with milk?
No, Mekenist should not be taken with milk or any calcium product because calcium may bind to the drug and lower its absorption rate in body. That may also affect in effective action of the drug.
What are the commonly observed side effects of Mekinist 2mg Tablet (Trametinib)?
The most common side effects of this medicine include Diarrhea, Headache, Tiredness, Mouth sores, Muscle or joint pain, Stomach pain, and difficulty breathing. It is advised to go for regular liver function tests to examine the liver function.
Who should avoid taking Mekinist 2mg Tablet (Trametinib)?
People diagnosed with severe liver and kidney disorders are advised to consult their healthcare professionals before taking this medicine.
Marketer Details
Novartis
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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