Leucovorin Calcium Injection (Calcium Leucovorin)
Prescription RequiredManufactured By
Fresenius kabi
Pack Of
1
Salt Composition
Calcium Leucovorin
Storage
Keep in cold place
ALL SUBSTITUTES
Leucovorin Calcium 50mg Injection
Overview
Leucovorin calcium injection (calcium leucovorin) is a supportive medication. Doctors prescribed this injection to prevent the harmful effects of methotrexate therapy (anticancer medication). It contains calcium leucovorin as an active ingredient. The injection works by providing the body a form of folic acid that helps protect healthy cells from the toxic effects of chemotherapy drugs.
Simultaneously, it enhances the action of some anticancer medicines and makes the treatment more effective. Patients are advised to follow all safety instructions carefully, provided by their doctor.
Quick Product Facts
| Field | Publication wording |
|---|---|
| Brand | leucovorin calcium |
| Generic / Active Ingredient | Calcium Leucovorin |
| Strength | 50 |
| Dosage Form | Injection |
| Manufacturer / Marketer | fresenius kabi |
| Pack Size | 1 |
| Prescription Required | Yes |
| Therapeutic Categories | Cancer Medicines |
| Uses | Chemotherapy |
Uses and Indications
Chemotherapy
Side Effects of Leucovorin Calcium Injection
Leucovorin Calcium Injection may cause some unwanted effects along with its desired benefits. However, not everyone experiences them, but if they persist or worsen, patients should consult their doctor immediately:
● Nausea or vomiting
● Diarrhea
● Allergic reactions (rash, itching, swelling)
● Fever
● Injection site reactions
Leucovorin Calcium Injection Dosage and How To Take It
Dosage depends on the patient's weight, height, and type of treatment. Leucovorin calcium injection (calcium leucovorin) is given intravenously (into a vein) under the supervision of a healthcare professional in a hospital or clinical setting.
Do not self-administer, as improper use may cause serious side effects.
Safety Advice for Leucovorin Calcium Injection
- ● Alcohol: Avoid alcohol while using leucovorin injection, as it may interfere with recovery.
- ● Driving: Leucovorin injection does not affect the ability to drive, but if you feel dizziness and other loss of vision, then avoid driving.
- ● Pregnancy: Leucovorin calcium injection is only used by pregnant women when prescribed under a doctor's prescription.
- ● Breastfeeding: Consult the healthcare expert before using Leucovorin Calcium Injection (calcium leucovorin), as safety data is limited.
- ● Kidney: Dose adjustment is required while taking the leucovorin calcium injection to ensure safety.
- ● Liver: Leucovorin injection may interfere with liver function. It is necessary to take safety precautions.
FAQs About Leucovorin Calcium Injection
1. Is Leucovorin Calcium Injection (Calcium Leucovorin) a chemotherapy drug?
No, Leucovorin calcium injection is not a chemotherapy drug, but it is a supportive medication that helps protect healthy cells and reduce the toxicity of methotrexate therapy.
2. How quickly does it start working?
Leucovorin calcium injection is working soon just after administration, especially during chemotherapy, where it enhances the effectiveness of certain anticancer medicines.
3. Is diabetic patient use Leucovorin Calcium Injection (Calcium Leucovorin)?
Yes, leucovorin is easily taken by diabetic patients if it is prescribed by medical supervision. It is better to inform the doctor about any previous treatment to avoid complications during the treatment.
4. How long does Leucovorin calcium Injection show result?
The leucovorin calcium injection's overall response may vary depending on the patient’s condition and type of treatment. Add it to your schedule as long as the doctor recommends it.
5. What medical advice should I follow during the treatment?
Patients should strictly follow the doctor's instructions while using the leucovorin calcium injection. Do not miss the schedule or stop the medicine without a healthcare professional.
References
● Pont, L. O., Cheung, A. P., & Lim, P. (1979). Calcium leucovorin. In Analytical profiles of drug substances (Vol. 8, pp. 315-350). Academic press.
● Gonyeau, M. J., & Yuen, D. W. (2010). A clinical review of statins and cancer: helpful or harmful?. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 30(2), 177-194.
● Hamed, K. M., Dighriri, I. M., Baomar, A. F., Alharthy, B. T., Alenazi, F. E., Alali, G. H., ... & Alzahrani, S. (2022). Overview of methotrexate toxicity: a comprehensive literature review. Cureus, 14(9).
● Conway, R., & Carey, J. J. (2017). Risk of liver disease in methotrexate treated patients. World journal of hepatology, 9(26), 1092.
● Solomon, D. H., Glynn, R. J., Karlson, E. W., Lu, F., Corrigan, C., Colls, J., ... & Ridker, P. M. (2020). Adverse effects of low-dose methotrexate: a randomized trial. Annals of internal medicine, 172(6), 369-380.
Marketer Details
Fresenius kabi
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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