Ledihep Tablet (Sofosbuvir (400mg) + Ledipasvir (90mg))
Prescription RequiredManufactured By
Zydus heptiza
Pack Of
28
Salt Composition
Sofosbuvir (400mg) + Ledipasvir (90mg)
Storage
Keep in cold place
Overview
Ledihep Tablet is an antiviral medicine. It is prescribed to treat chronic hepatitis C virus (HCV) infection. It is a combination of two antiviral medicines such as ledipasvir 90mg and sofosbuvir 400mg. It works by lowering the viral load in the body and eliminating the virus from the blood over time. It commonly used to reats HCV genotypes 1, 4, 5, and 6. It should be taken in dose and duration as advice by the doctor. Don't take more than the recommended dose.
Quick Product Facts
| Field | Publication wording |
|---|---|
| Brand | ledihep |
| Generic / Active Ingredient | Sofosbuvir/Ledipasvir |
| Strength | 90 |
| Dosage Form | Tablet |
| Manufacturer / Marketer | zydus heptiza |
| Pack Size | 28 |
| Prescription Required | Yes |
| Therapeutic Categories | Hepatitis Medicines |
| Uses | hepatitis |
Uses and Indications
Hepatitis C
Side Effects of Ledihep Tablet
Side effects are undesirable symptoms that can result from any medical treatment. Like any other medicine, Ledihep Tablet(ledipasvir and sofosbuvir) also causes some adverse impact on the body, most of which are resolved without any medical attention.
Some common side effects include:
Common
● Headache
● Tiredness
● Rashes
Serious
● Allergic reactions
Seek medical attention in case of any unusual or severe side effects immediately.
Ledihep Tablet Dosage and How To Take It
Doctor determines the dosage and duration of Ledihep Tablet(ledipasvir and sofosbuvir) as per the type of disease and overall health condition of the patients. Swallow it as a whole with water. Do not chew, crush or break it. This tablet may be taken with or without food. In case of an overdose of this tablet, contact your doctor or any healthcare provider and seek medical attention immediately.
Safety Advice for Ledihep Tablet
- ● Alcohol: Avoid the consumption of alcohol while taking Ledihep Tablet(ledipasvir and sofosbuvir), as alcohol can decrease the effectiveness of the medicine as well as worsen the symptoms.
- ● Pregnancy: Do not take Ledihep Tablet without consulting the doctor in case of pregnancy, as it can be unsafe to take it during this period.
- ● Breastfeeding: Breastfeeding women should discuss the potential risks and benefits of the Ledihep Tablet(ledipasvir and sofosbuvir) with their healthcare provider before starting treatment.
- ● Driving: Ledihep Tablet may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving.
- ● Kidney: Share your medical history with the doctor before starting the Ledihep Tablet(ledipasvir and sofosbuvir). Do not take it without consulting a doctor if you have any kidney related issue.
- ● Liver: Share your medical history with the doctor before starting the Ledihep Tablet(ledipasvir and sofosbuvir). Do not take it without consulting a doctor if you have any liver related issue.
FAQs About Ledihep Tablet
What are the uses of Ledihep Tablet(ledipasvir and sofosbuvir)?
It is an antiviral medicine used in the treatment of chronic hepatitis C virus (HCV) infection as prescribed by the doctor.
Is it safe to take the Ledihep Tablet(ledipasvir and sofosbuvir) during pregnancy or breastfeeding?
Consumption of Ledihep Tablet during pregnancy or breastfeeding is considered to be unsafe, especially without doctor's advice.
Is it safe to take other medicine with Ledihep Tablet?
As Ledihep Tablet(ledipasvir and sofosbuvir) can interact with some medicine. It is advisable to inform your doctor about any medicine you are taking.
What are the common side effects of Ledihep Tablet?
There are some common side effects of taking Ledihep Tablet(ledipasvir and sofosbuvir) such as headache, nausea, vomiting, fatigue, stomach pain, etc.
How to take Ledihep Tablet(ledipasvir and sofosbuvir)?
Ledihep Tablet tablet may be taken with or without food and should be swallowed with water as prescribed by the doctor.
References
● Lawitz, E., Poordad, F. F., Pang, P. S., Hyland, R. H., Ding, X., Mo, H., ... & Membreno, F. E. (2014). Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial. The Lancet, 383(9916), 515-523.
● Colombo, M., Aghemo, A., Liu, H., Zhang, J., Dvory-Sobol, H., Hyland, R., ... & Pol, S. (2017). Treatment with ledipasvir–sofosbuvir for 12 or 24 weeks in kidney transplant recipients with chronic hepatitis C virus genotype 1 or 4 infection: a randomized trial. Annals of internal medicine, 166(2), 109-117.
● Scott, L. J. (2018). Ledipasvir/sofosbuvir: a review in chronic hepatitis C. Drugs, 78(2), 245-256.
● German, P., Pang, P. S., Fang, L., Chung, D., & Mathias, A. (2014). Drug-Drug Interaction Profile Of The Fixed-Dose Combination Tablet Ledipasvir/Sofosbuvir: 1976. Hepatology, 60, 1162A.
● German, P., Mathias, A., Brainard, D. M., & Kearney, B. P. (2018). Drug–drug interaction profile of the fixed-dose combination tablet regimen ledipasvir/sofosbuvir. Clinical pharmacokinetics, 57(11), 1369-1383.
● Cada, D. J., Baker, D. E., & Bindler, R. J. (2015). Ledipasvir/sofosbuvir. Hospital pharmacy, 50(3), 224-234.
Marketer Details
Zydus heptiza
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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