L Asgen 10000 IU Injection (L- Asparaginase)
Prescription RequiredManufactured By
Adley
Pack Of
1
Salt Composition
L- Asparaginase
Storage
Keep in cold place
ALL SUBSTITUTES
L Aspase 10000 IU Injection
L Ginase 10000 IU Injection
Overview
L Asgen 10000 IU Injection is a antineoplastic injection prescribed by the doctor to treat acute lymphoblastic leukemia (ALL) in patients aged 4 months and above, used as part of combination chemotherapy.
L Asgen Injection contains L-asparaginase that works by depleting asparagine, an essential amino acid that leukemic cells cannot synthesize adequately, starving them of nutrients needed for synthesis and inducing apoptosis. As a result, cancer cell growth decreases and eventually dies.
Quick Product Facts
| Field | Publication wording |
|---|---|
| Brand | l asgen |
| Generic / Active Ingredient | L- Asparaginase |
| Strength | 10000 |
| Dosage Form | Injection |
| Manufacturer / Marketer | adley |
| Pack Size | 1 |
| Prescription Required | Yes |
| Therapeutic Categories | Cancer Medicines |
| Uses | Unknown |
Uses and Indications
lymphoblastic leukemia
Side Effects of L Asgen 10000 IU Injection
L- Asparaginase 10000 IU Injection (L Asgen) contains chemical based salt. Like any other chemical-based drug, its chemical-based formula causes multiple negative effects. See your physician if these side effects persist for an extended period of time.
Common Side Effects of L Asgen 10000 IU Injection
● Headache
● Dizziness
● Pain or Swelling at the injection site
● Loss of Appetite
● Mouth Sores
● Muscle Pain
● Constipation
● Taste Change
● Difficulty in Swelling
● Breathlessness
● Edema
● Nausea
● Fever
● Fatigue
● Weight Gain
Serious Side Effects
- Severe Side Effects of L Asgen 10000 IU Injection
- ● Low Platelet Count
- ● Severe Infection
- ● Liver Function Impairment
- ● Allergic Reactions
- ● Nerve Damage
- ● Pancreatitis
- ● Severe Hyperglycemia
- ● Cerebral Thrombosis
L Asgen 10000 IU Injection Dosage and How To Take It
The exact dosage of L- Asparaginase 10000 IU Injection (L Asgen) depends on the type of cancer being treated, its stage, patient's weight as well as overall health of the body.
The prescribed dosage by the doctor is administered intravenously (into veins) or Intramuscularly (In Muscles) by a doctor or experienced nurse. Do not try to Self-Administer the injection.
L Asgen 10000 IU Injection Missed Dose
Safety Advice for L Asgen 10000 IU Injection
- 1. It is advisable not to consume alcohol while taking L- Asparaginase 10000 IU Injection (L Asgen) as it can worsen the side effects. It is advised to consult your doctor for further information.
- 2. L Asgen 10000 IU Injection is considered unsafe for pregnancy due to fetal harm and teratogenic nature. Please consult your doctor in such condition.
- 3. Breast Feeding is not advisable during the L- Asparaginase 10000 IU Injection (L Asgen) Course. Consult your Doctor for more information.
- 4. It is advisable not to drive, as you may feel dizzy after taking L Asgen 10000 IU administration.
- 5. Share your medical history related to kidney cancer or any other issue with your doctor before taking L Asgen 10000 IU Injection.
- 6. Notify your doctor about any liver disease or infection before starting L Asgen 10000 IU Injection course.
FAQs About L Asgen 10000 IU Injection
What is the ambient temperature to store L Asparaginase 10000 IU Injection (L Asgen)?
The ambient temperature to store L Asparaginase 10000 IU Injection (L Asgen) is 2-8 degree celcius.
How L Asgen 10000 IU Injection works?
L Asgen 10000 IU Injection contains L-asparaginase that works by depleting asparagine, an essential amino acid that leukemic cells cannot synthesize adequately, starving them of nutrients needed for synthesis and inducing apoptosis.
Safety tips to consider before administering L Asgen 10000 IU Injection?
The safety tips to consider before administering L Asgen Injection are keep it out of the reach of children, store it in ambient temperature as well as do not self administer the injection.
Is there any severe effect on the liver after administering L Asgen 10000 IU Injection?
Yes, administration of L Asgen 10000 IU Injection leads to severe side effect on liver that is Liver Function Impairment ( a rare disease of liver) and other liver function abnormalities.
What are the uses of L Asparaginase 10000 IU Injection (L Asgen)?
The use of L Asparaginase 10000 IU Injection (L Asgen)is to treat acute lymphoblastic leukemia (ALL) in patients aged 4 months and above, used as part of combination chemotherapy.
References
● Van Trimpont, M., Peeters, E., De Visser, Y., Schalk, A. M., Mondelaers, V., De Moerloose, B., ... & Van Vlierberghe, P. (2022). Novel insights on the use of L-asparaginase as an efficient and safe anti-cancer therapy. Cancers, 14(4), 902.
● Jaffe, N., Traggis, D., Das, L., Moloney, W. C., Hann, H. W., Kim, B. S., & Nair, R. (1971). L-asparaginase in the treatment of neoplastic diseases in children. Cancer research, 31(7), 942-949.
● Pagliardi, G. L., Gabutti, V., & Gavosto, F. (1973). Mechanism of action of L-asparaginase on the cell cycle and growth in acute lymphoblastic leukemia. Acta Haematologica, 50(5), 257-268.
● Narta, U. K., Kanwar, S. S., & Azmi, W. (2007). Pharmacological and clinical evaluation of L-asparaginase in the treatment of leukemia. Critical reviews in oncology/hematology, 61(3), 208-221.
Marketer Details
Adley
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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