Duovir 150mg Tablet (Lamivudine(150mg) and Zidovudine(300mg))
Prescription RequiredManufactured By
Cipla
Pack Of
60
Salt Composition
Lamivudine(150mg) and Zidovudine(300mg)
Storage
Keep in cold place
Overview
Duovir 150mg Tablet is a combination of two antiviral drugs that is used to treat Human Immunodeficiency Virus (HIV) Infection. Duovir Tablet contains the salts Lamivudine (150 mg) and Zidovudine (300 mg).
Lamivudine and Zidovudine belong to a class of medicines known as nucleoside reverse transcriptase inhibitors (NRTIs), which act by inhibiting the reverse transcriptase enzyme vital for HIV replication.
Both the drugs Inhibits reverse transcriptase, stopping HIV replication and reducing viral load. It also boosts the immune system that helps in controlling the infection and lowering the risk of AIDS.
Quick Product Facts
| Field | Publication wording |
|---|---|
| Brand | duovir |
| Generic / Active Ingredient | Lamivudine and Zidovudine |
| Strength | 150 |
| Dosage Form | Tablet |
| Manufacturer / Marketer | cipla |
| Pack Size | 60 |
| Prescription Required | Yes |
| Therapeutic Categories | HIV Medicines |
| Uses | HIV |
Uses and Indications
HIV
Side Effects of Duovir 150mg Tablet
Like any other chemical based medication, it also has certain common side effects. Consult your doctor, if side effects persist for longer period of time.
Common Side Effects of Lamivudine + Zidovudine Tablet (Duovir):
● Headache
● Fatigue or weakness
● Nausea
● Vomiting
● Diarrhea
● Cough
● Rash or itchy skin
● Muscle pain or joint pain
● Insomnia (difficulty sleeping)
● Fever
● Nasal congestion (stuffy nose)
● Abdominal pain and cramps
● Loss or decreased appetite
Common or Clinically Frequent Side Effects
- Serious Side Effects:
- ● Severe skin reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis
- ● Lactic acidosis
- ● Muscle breakdown
- ● Severe liver problems
- ● Blood disorders like anemia, neutropenia (low white blood cells), thrombocytopenia (low platelets)
- ● Severe Allergic reactions
Duovir 150mg Tablet Dosage and How To Take It
Duovir 150mg Tablet (Lamivudine + Zidovudine) is taken orally twice a day with or without food. This is the usual starting dosage for adults but can vary later based on the infection progression and overall response of the body.
Tablets should be consumed whole as it is without breaking, chewing or biting to maintain their efficacy. For exact dosage, contact your doctor. Don't miss the dosage and remain consistent about medication.
Duovir 150mg Tablet Missed Dose
Safety Advice for Duovir 150mg Tablet
- 1. It is generally advice to avoid or limit alcohol consumption. Alcohol can affect the working mechanism of Lamivudine + Zidovudine Tablet (Duovir) as well as there are possibility of reducing effectiveness. For more details and approvals, Consult your Doctor.
- 2. Duovir Tablet is not prescribed or allowed at the time of pregnancy. It causes embryo-fetal toxicity. Consult your doctor in case of accidental pregnancy, treatment or further risks.
- 3. In general there is no data related to Duovir 150mg and its effect on breast feeding. But it is generally not advisable during the medication course. Consult your Doctor for more information.
- 4. It is advisable not to drive, as you may feel dizzy and can come across blurred vision after taking Duovir 150mg Tablet.
- 5. Share your medical history details related to kidney cancer or any other disease with your doctor before taking Lamivudine + Zidovudine Tablet (Duovir).
- 6. Notify your doctor about any liver disease or infection before starting Duovir Tablet course. As it can cause serious liver damage.
FAQs About Duovir 150mg Tablet
What is the ideal temperature to store Lamivudine 150mg + Zidovudine 300mg Tablet (Duovir)?
The ideal temperature to store Lamivudine 150mg + Zidovudine 300mg Tablet (Duovir) is at room temperature, specifically between 15-30 degree celcius.
Can Duovir Tablet be given with any other medicine?
Yes, Duovir Tablet can be given with other medicines. Consult your doctor for drug interaction knowledge and personalized guidance.
What is the use of Lamivudine 150mg + Zidovudine 300mg Tablet (Duovir?
Lamivudine 150mg + Zidovudine 300mg Tablet (Duovir) is used to treat Human Immunodeficiency Virus (HIV) Infection.
What all antiviral drug form Duovir Tablet?
Lamivudine (150 mg) and Zidovudine (300 mg) antivirals forms the Duovir Tablet.
What is the basic mechanism of Duovir 150mg Tablet (Lamivudine + Zidovudine)?
Duovir 150mg Tablet Inhibits reverse transcriptase, stopping HIV replication and reducing viral load.
References
● Eron, J. J., Benoit, S. L., Jemsek, J., MacArthur, R. D., Santana, J., Quinn, J. B., ... & Rubin, M. (1995). Treatment with lamivudine, zidovudine, or both in HIV-positive patients with 200 to 500 CD4+ cells per cubic millimeter. New England Journal of Medicine, 333(25), 1662-1669.
● Staszewski, S. (1995). Zidovudine and lamivudine: results of phase III studies. JAIDS Journal of Acquired Immune Deficiency Syndromes, 10(1), S58.
● Staszewski, S., Loveday, C., Picazo, J. J., Dellamonica, P., Skinhøj, P., Johnson, M. A., ... & McDade, H. (1996). Safety and efficacy of lamivudine-zidovudine combination therapy in zidovudine-experienced patients: a randomized controlled comparison with zidovudine monotherapy. Jama, 276(2), 111-117.
● Juan, C., Jiang, X., & Qiang, Z. (2014). Side effects and tolerability of post-exposure prophylaxis with zidovudine, lamivudine, and lopinavir/ritonavir: a comparative study with HIV/AIDS patients. Chinese medical journal, 127(14), 2632-2636.
Marketer Details
Cipla
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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