Decarb 500mg Injection (Dacarbazine)
Prescription RequiredManufactured By
Cipla
Pack Of
1
Salt Composition
Dacarbazine
Storage
Keep in cold place
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Overview
Decarb 500mg Injection is an anticancer chemotherapeutic injection prescribed by the doctor to treat metastatic malignant melanoma and Hodgkin's lymphoma.
Deacrb injection contains dacarbazine as its active salt. Dacarbazine is activated in the liver to MITC (monomethyl triazeno imidazole carboxamide). This active form methylates DNA and inhibit the cancer cell multiplication in the body. This induces self cell death phenomena in the cancer cells. As a result, it causes cancer cell death and ultimately cures cancer.
Quick Product Facts
| Field | Publication wording |
|---|---|
| Brand | decarb |
| Generic / Active Ingredient | Dacarbazine |
| Strength | 500 |
| Dosage Form | Injection |
| Manufacturer / Marketer | cipla |
| Pack Size | 1 |
| Prescription Required | Yes |
| Therapeutic Categories | Cancer Medicines |
| Uses | Skin Cancer |
Uses and Indications
Skin Cancer
Side Effects of Decarb 500mg Injection
Dacarbazine 500mg Injection (Decarb) is a chemical salt based anticancer injection. Its salt in reaction with the body leads to numerous side effects like any other chemical medication. Symptoms may vary from mild to severe. If these side effects remain for longer period of time, consult your doctor immediately.
Common Side Effects of Decarb 500mg Injection:
● Hair loss
● Mouth Sores
● Nausea
● Weakness
● Low Red, White and Platelets Blood Cell Count
● Muscle Pain
● Injection Site reactions such as Redness, Itching etc
● Vomiting
● Flu Like Symptoms
● Photosensitivity
Serious Side Effects
- Severe Side Effects of Decarb 500mg Injection:
- ● Febrile Nutropenia
- ● Allergic Reactions
- ● Peripheral Neuropathy
- ● Liver Toxicity
- ● Secondary Cancer or Diseases
- ● Severe Bone Suppression
- ● Anaphylaxis
Decarb 500mg Injection Dosage and How To Take It
Dacarbazine 500mg Injection (Decarb) is administered intravenously (In Veins) by a doctor or an experienced nurse. It is advice not to self administer the injection on your own. For personalized dosage ask your doctor about the same. As Dosage is entirely based on the body surface area, type of cancer, its stage as well as patient's overall health.
Safety Advice for Decarb 500mg Injection
- It is advisable not to consume alcohol while taking Decarb 500mg Injection as it can worsen the side effects. It is advised to consult your doctor for further information.
- 2. Dacarbazine 500mg Injection (Decarb) is considered unsafe during pregnancy due to fetal harm. Please consult your doctor in such condition.
- 3. Breast Feeding is not advisable during the Decarb 500mg Injection treatment Course. Consult your Doctor for more information.
- 4. It is advisable not to drive, as you may feel dizzy after taking Decarb 500mg Injection.
- 5. Share your medical history with your doctor in case of kidney disease before taking Decarb 500mg Injection.
- 6. Notify your doctor about any liver disease or infection before starting Decarb 500mg Injection course.
FAQs About Decarb 500mg Injection
What type of cancer is treated using Dacarbazine 500mg Injection (Decarb)?
Dacarbazine 500mg Injection (Decarb) treats metastatic malignant melanoma and Hodgkin's lymphoma.
Can Decarb 500mg Injection be given with any other medicine?
Yes, Decarb 500mg Injection can be given with other chemotherapeutic drugs or injection based on cancer type and its stage to increase effectiveness.Strictly under medical supervision.
How Decarb 500mg Injection is given to cancer patients?
Decarb 500mg Injection is given intravenously (In veins) to cancer patients by a doctor or experienced nurse. Kindly do not try to self administer the injection.
What should I do if I experience severe side effects with Decarb 500mg Injection?
Decarb 500mg Injection can cause severe side effects such as kidney problems, liver problems, blood in urine, jaundice etc. Notify your doctor immediately as it may require withholding or stopping of treatment.
Is Decarb 500mg Injection advisable during Pregnancy?
Decarb 500mg Injection cause harm to growing fetus. Thus, it is not recommended during pregnancy for treatment.
References
● Carter, S. K. (1976). Dacarbazine. International Journal of Dermatology, 15(1).
● Ugurel, S., Paschen, A., & Becker, J. C. (2013). Dacarbazine in melanoma: from a chemotherapeutic drug to an immunomodulating agent. Journal of Investigative Dermatology, 133(2), 289-292.
● Al-Badr, A. A., & Alodhaib, M. M. (2016). Dacarbazine. Profiles of Drug Substances, Excipients and Related Methodology, 41, 323-377.
● Teimouri, F., Nikfar, S., & Abdollahi, M. (2013). Efficacy and side effects of dacarbazine in comparison with temozolomide in the treatment of malignant melanoma: a meta-analysis consisting of 1314 patients. Melanoma research, 23(5), 381-389.
Marketer Details
Cipla
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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