Crizalk 250mg Capsule (Crizotinib)
Prescription RequiredManufactured By
Pfizer
Pack Of
60
Salt Composition
Crizotinib
Storage
Keep in cold place
Overview
Crizalk 250mg Capsule (Crizotinib) is a targeted cancer treatment. This prescription-based medicine is used to treat non-small cell lung cancer. Crizotinib is an active salt composition of a drug and belongs to the drug class of tyrosine kinase inhibitors (TKIs).
It works by inhibiting a specific tyrosine kinase enzyme; as a result, it slows or stops the growth of cancer cells in the body. The medicine should be taken under the strict supervision of a doctor.
Quick Product Facts
| Field | Publication wording |
|---|---|
| Brand | crizalk |
| Generic / Active Ingredient | Crizotinib |
| Strength | 250 |
| Dosage Form | Capsule |
| Manufacturer / Marketer | pfizer |
| Pack Size | 60 |
| Prescription Required | Yes |
| Therapeutic Categories | Cancer Medicines |
| Uses | Lung Cancer |
Uses and Indications
Lung cancer
Side Effects of Crizalk 250mg Capsule
Every medicine causes side effects; some of them may resolve on their own, and some need proper medical attention to treat.
Common symptoms include:
● Fever
● Constipation
● Nausea
● Increased liver enzymes
● Decreased appetite, tiredness
● Dizziness
● Low heart rate.
● Swelling of the lungs.
● Breathlessness
● Cough with or without mucus
Crizalk 250mg Capsule Dosage and How To Take It
Crizalk 250mg Capsule (Crizotinib) should be taken exactly as prescribed by the healthcare professional at the fixed time every day. Take the medicine twice or daily with or without food as recommended by the healthcare professional.
Do not stop or change the dose without consulting a doctor, as this may affect treatment effectiveness.
Safety Advice for Crizalk 250mg Capsule
- ● Alcohol: Alcohol can worsen the side effects like low blood pressure and dizziness. Try to limit or avoid intake of alcohol while using the Crizotinib 250mg capsule (Crizalk).
- ● Driving: Crizalk 250mg Capsule may cause dizziness and drowsiness in some patients. Avoid driving, as it affects the eyesight and makes driving unsafe.
- ● Pregnancy: Crizalk 250mg Capsule (Crizotinib) is not recommended for pregnant women, as it causes serious health complications to the unborn baby.
- ● Breastfeeding: The Crizotinib 250mg capsule (Crizalk) should be taken with caution during breastfeeding. It is always necessary to take consultation from a physician and seek medical attention immediately in case of any abnormal reaction in the infant.
- ● Kidney: Inform the doctor before taking the Crizalk 250mg capsule if you have any kidney problems to adjust the dose according to the patient's health condition.
- ● Liver: Crizalk 250mg Capsule (Crizotinib) should be used with caution in patients with liver problems, as it may require dose adjustment.
FAQs About Crizalk 250mg Capsule
1. How should I take Crizalk 250mg Capsule (Crizotinib)?
Take the Crizalk 250mg capsule once or twice daily as prescribed by the doctor. It should be taken with or without food at the same time every day to enhance the effectiveness of the treatment.
2. What is the active drug composition of Crizotinib 250mg Capsule (Crizalk)?
Crizalk 250mg Capsule contains an active ingredient, Crizotinib, that works by blocking the specific protein called tyrosine kinase enzymes, which are responsible for the growth of cancer cells in the body.
3. Can I stop taking Crizalk 250mg Capsule once my symptoms getting normal?
No, you should not stop the Crizalk 250mg capsule on your own, even if you feel well. Consult the doctor before stopping or changing the dose.
4. Is Crizalk 250mg Capsule (Crizotinib) cause any side effects?
Patients should notice these side effects of the Crizalk 250mg capsule to detect the disease early and immediately take medical help if they worsen:
- Headache
- Dizziness or drowsiness
- Fatigue or tiredness
- Nausea or mild stomach discomfort
5. How long should I use Crizotinib 250mg Capsule (Crizalk)?
Use the Crizalk 250mg capsule until the doctor advises you to stop it. Do not self administer the medication to avoid complications during the treatment.
References
● Sahu, A., Prabhash, K., Noronha, V., Joshi, A., & Desai, S. (2013). Crizotinib: A comprehensive review. South Asian journal of cancer, 2(2), 91.
● Heigener, D. F., & Reck, M. (2018). Crizotinib. Small molecules in oncology, 57-65.
● Shaw, A. T., Kim, D. W., Nakagawa, K., Seto, T., Crinó, L., Ahn, M. J., ... & Jänne, P. A. (2013). Crizotinib versus chemotherapy in advanced ALK-positive lung cancer. New England Journal of Medicine, 368(25), 2385-2394.
● Forde, P. M., & Rudin, C. M. (2012). Crizotinib in the treatment of non-small-cell lung cancer. Expert opinion on pharmacotherapy, 13(8), 1195-1201.
● Shaw, A. T., Bauer, T. M., de Marinis, F., Felip, E., Goto, Y., Liu, G., ... & Solomon, B. J. (2020). First-line lorlatinib or crizotinib in advanced ALK-positive lung cancer. New England Journal of Medicine, 383(21), 2018-2029.
Marketer Details
Pfizer
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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