Cazanat 20mg Tablet (Cabozantinib)
Prescription RequiredManufactured By
Natco
Pack Of
30
Salt Composition
Cabozantinib
Storage
Keep in cold place
Overview
The Cazanat 20mg tablet (cabozantinib) is a targeted therapy that is prescribed by a healthcare professional. The medicine is used to treat kidney, liver, and thyroid cancer. Its active salt composition, cabozantinib, belongs to a class of medicine called tyrosine kinase inhibitors (TKIs).
It works by inhibiting multiple tyrosine kinase inhibitors, including VEGFR, MET, and RET, that signal cancer cells to multiply rapidly. It prevents the tumor from developing its own blood vessels, essentially starving the tumor of nutrients and oxygen.
Quick Product Facts
| Field | Publication wording |
|---|---|
| Brand | cazanat |
| Generic / Active Ingredient | Cabozantinib |
| Strength | 20 |
| Dosage Form | Tablet |
| Manufacturer / Marketer | Natco |
| Pack Size | 30 |
| Prescription Required | Yes |
| Therapeutic Categories | Cancer Medicines |
| Uses | kidney cancer |
Uses and Indications
Kidney Cancer
Side Effects of Cazanat 20mg Tablet
Most of the side effects of the Cazanat 20mg tablet (cabozantinib) are manageable, and some require proper medical attention. Doctor consultation is highly required if any of these symptoms persist or worsen or if you experience unusual reactions during the treatment:
● Dehydration
● Difficulty swallowing
● Ringing in the ears
● Blood clots in the veins
● Fluctuation in the blood sugar levels
● The lower level of albumin
● Electrolyte imbalance
● Increased levels of liver enzymes
● Elevated cholesterol levels in the blood
● Hair loss
● Changes in hair color
● Muscle spasm
● Skin thickening
Cazanat 20mg Tablet Dosage and How To Take It
Taking the Cabozantinib 20mg Tablet (Cazanat) exactly as prescribed by the doctor. Do not overdose the medicine to make up for the missed one, as this may cause several side effects.
Consume on an empty stomach, avoid food 2 hours before and 1 hour after. Swallow the tablet whole with water; do not crush, chew, or break it. Take it at the same time every day to enhance the effectiveness of the treatment.
Safety Advice for Cazanat 20mg Tablet
- ● Alcohol: Do not consume alcohol, as the chances of suffering from lactic acidosis become higher, which is a very uncommon and critical adverse reaction while using the Cabozantinib 20mg Tablet (Cazanat). Take an in-depth discussion with your physician regarding how much alcohol consumption is safe for you while taking the medicine.
- ● Driving: The Cazanat 20mg tablet does not usually affect alertness in some patients. However, do not drive if you experience low blood sugar, and consult the healthcare professional for further guidance.
- ● Pregnancy: The pregnant mother is not supposed to use the Cazanat 20mg tablet (cabozantinib) because it can harm the child. It can only be administered after thorough analysis and prescription by a physician.
- ● Breastfeeding: The Cabozantinib 20mg Tablet (Cazanat) may have adverse effects on the breastfeeding infant, as the drug may be secreted in breast milk. It is recommended that you seek medical advice before taking this drug while breastfeeding.
- ● Kidney: Patients with kidney diseases are advised to speak with a medical expert before using Cazanat 20mg Tablet for safety reasons.
- ● Liver: Liver patients should avoid taking the Cazanat 20mg tablet (Cabozantinib), as the medicine may worsen liver function or lead to serious complications. Always consult a healthcare professional before use.
FAQs About Cazanat 20mg Tablet
1. What is Cabozantinib 20mg Tablet (Cazanat) used for?
The medicine is used in the treatment of kidney, liver, or thyroid cancer.
2. What is the active ingredient of Cazanat 20mg tablet (Cabozantinib)?
The medicine contains a salt composition of cabozantinib, which helps slow tumor growth and prevent the spreading of cancer cells in the body.
3. Can Cabozantinib 20mg Tablet (Cazanat) cure cancer?
Medicine does not cure cancer permanently but helps control its growth and spread in the body.
4. Can I take Cazanat 20mg tablet (Cabozantinib) at night?
Yes, Cazanat 20mg Tablet can be taken at night, but consistently with the daily schedule at the fixed time under doctor guidance.
5. What should I do if I miss a dose?
Take it as soon as you remember unless it is close to your next dose, but do not double up. It is better to consult the doctor about dose and duration to ensure safe and effective treatment.
References
● Lacy, S. A., Miles, D. R., & Nguyen, L. T. (2017). Clinical pharmacokinetics and pharmacodynamics of cabozantinib. Clinical pharmacokinetics, 56(5), 477-491.
● Abou-Alfa, G. K., Meyer, T., Cheng, A. L., El-Khoueiry, A. B., Rimassa, L., Ryoo, B. Y., ... & Kelley, R. K. (2018). Cabozantinib in patients with advanced and progressing hepatocellular carcinoma. New England Journal of Medicine, 379(1), 54-63.
● El-Khoueiry, A. B., Hanna, D. L., Llovet, J., & Kelley, R. K. (2021). Cabozantinib: An evolving therapy for hepatocellular carcinoma. Cancer Treatment Reviews, 98, 102221.
● Choueiri, T. K., Escudier, B., Powles, T., Mainwaring, P. N., Rini, B. I., Donskov, F., ... & Motzer, R. J. (2015). Cabozantinib versus everolimus in advanced renal-cell carcinoma. New England Journal of Medicine, 373(19), 1814-1823.
● Yakes, F. M., Chen, J., Tan, J., Yamaguchi, K., Shi, Y., Yu, P., ... & Joly, A. H. (2011). Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth. Molecular cancer therapeutics, 10(12), 2298-2308.
Marketer Details
Natco
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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