Calquence 100mg Capsule (Acalabrutinib)
Prescription RequiredManufactured By
Astra Zeneca
Pack Of
60
Salt Composition
Acalabrutinib
Storage
Keep in cold place
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Acaluxen 100mg Capsule
Overview
Calquence 100mg Capsule (Acalabrutinib) is a prescription-based anticancer medicine used in the treatment of Mantle cell lymphoma (MCL), Chronic lymphocytic leukaemia (CLL), and Small lymphocytic lymphoma (SLL). The active ingredient of the Calquence is Acalabrutinib which belongs to the drug class of Bruton's tyrosine kinase (BTK) inhibitors.
The growth of cancer cells is uncontrollable and abnormal in the human body. It is difficult to diagnose cancer in the early stages as there are no noticeable symptoms. When diagnosed in advanced stages, only the symptoms of the disease can be reduced. Calquence Capsule are usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
Indication
Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer
Side Effects
The human body shows undesired symptoms after taking Calquence 100mg Capsule (Acalabrutinib). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Some of the common side effects of Calquence Capsule are mentioned below:
●Fatigue
●Nausea
●Diarrhea
●Headache
●Rash or itching
●Muscle and joint pain
●Bruising or bleeding easily
●Upper respiratory tract infection
Common Side Effects
- ●Kidney failure
- ●High blood pressure
- ●Infections (pneumonia and sepsis)
- ●Bleeding problems (bruising or bleeding)
- ●Heart problems (irregular heartbeat and chest pain)
How To Use
Calquence 100mg Capsule (Acalabrutinib) is a prescription-based anticancer drug that should be administered orally. It is advised to take this capsule after consulting your healthcare expert. This capsule should be swallowed as a whole with water. Don't crush, chew, or break it. It can be taken with or without food. Never skip a dose or double dose.
Missed Doses
Instructions if you miss a dose
Reference
Wang, M., Rule, S., Zinzani, P. L., Goy, A., Casasnovas, O., Smith, S. D., ... & Jurczak, W. (2018). Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial. The Lancet, 391(10121), 659-667.
Byrd, J. C., Woyach, J. A., Furman, R. R., Martin, P., O’Brien, S., Brown, J. R., ... & Wierda, W. G. (2021). Acalabrutinib in treatment-naive chronic lymphocytic leukemia. Blood, The Journal of the American Society of Hematology, 137(24), 3327-3338.
Byrd, J. C., Harrington, B., O’Brien, S., Jones, J. A., Schuh, A., Devereux, S., ... & Furman, R. R. (2016). Acalabrutinib (ACP-196) in relapsed chronic lymphocytic leukemia. New England Journal of Medicine, 374(4), 323-332.
Markham, A., & Dhillon, S. (2018). Acalabrutinib: first global approval. Drugs, 78(1), 139-145.
Wu, J., Zhang, M., & Liu, D. (2016). Acalabrutinib (ACP-196): a selective second-generation BTK inhibitor. Journal of hematology & oncology, 9(1), 21
Safety Advice
- ● Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to
- consume alcohol while taking Calquence 100mg Capsule (Acalabrutinib). It is advised to consult your doctor for further information.
- ● Pregnancy: Calquence 100mg Capsule (Acalabrutinib) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- ● Breastfeeding: Calquence 100mg Capsule (Acalabrutinib) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- ● Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Calquence 100mg Capsule (Acalabrutinib).
- ● Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Calquence 100mg Capsule (Acalabrutinib).
- ● Liver: Inform your doctor before starting Calquence 100mg Capsule (Acalabrutinib) if you have liver disease to avoid any serious side effects.
FAQs
Is it safe to take Calquence 100mg Capsule (Acalabrutinib) for a person with history of bleeding disorders?
This medicine may elevate the risk of bleeding in patients with bleeding disorders while taking Calquence Capsule (Acalabrutinib). It is advised to consult your healthcare provider before starting treatment with this anticancer medicine.
Can a person with a heart disorder take Calquence 100mg Capsule (Acalabrutinib)?
Taking these capsule may result in heart problems such as irregular heartbeat and chest pain. Anyone with a history of heart disease should be closely monitored by a doctor while taking Calquence.
What is the effect of Calquence 100mg Capsule (Acalabrutinib) on the blood?
This medicine may decrease RBCs, WBCs, and platelets count in the blood. It results in anemia, frequent infections, and high risk of bleeding. The doctor will examine for blood cell count frequently while taking Calquence.
Is it safe for a diabetic person to take Calquence 100mg Capsule (Acalabrutinib)?
This medicine can be taken by patients with diabetes under a doctor's prescription. It is crucial to monitor the level of blood sugar levels while taking this medication. There are chances that it may elevate blood sugar levels in some patients, In such cases the dosage of medicine or insulin is given accordingly.
Can women safely take Calquence 100mg Capsule (Acalabrutinib) if planning for pregnancy?
If you are planning for pregnancy, it is advisable to consult your doctor in such cases. Use effective birth control methods to avoid pregnancy while undergoing treatment with this medicine, as it may harm the unborn baby.
Marketer Details
Astra Zeneca
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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