Bicatero 50mg Tablet (Bicalutamide)

Bicatero 50mg Tablet is a non-steroidal antiandrogen medicine that acts as an androgen receptor inhibitor. This has an active ingredient, bicalutamide, that treats advanced or metastatic prostate cancer. This is prescribed in combination with a luteinizing hormone-releasing hormone (LHRH) analog as part of androgen-deprivation therapy. Bicalutamide 50mg tablet works by blocking male sex hormones, specifically testosterone, which can stimulate the growth of prostate cancer cells. This competitively binds to androgen receptors to prevent the androgen from activating these receptors and reducing the androgen-driven growth of prostate cancer cells.

The tablet is taken orally and is consumed with or without food. Doctors prescribe one tablet a day but ensure to take it at the same time to maintain consistency. The dosage of the bicalutamide 50mg tablet is determined according to the indication, the patient's condition, and the treatment response. Patients are advised not to change the dosage because it can lead to severe side effects.

Common side effects can include hot flashes, pain, weakness or fatigue, constipation, nausea, diarrhea, infection, swelling of the limbs, difficulty breathing, blood in the urine, and anemia. Also, they can undergo breast tenderness or enlargement during the treatment. Most of bicalutamide 50mg tablet side effects can leave when the body adapts to the medicine. However, if any side effects persist, inform your doctor immediately.

The medicine is generally not indicated for women or children. Patients must list all medicines, supplements, and herbal products that they are taking. The bicalutamide 50mg tablet must be used under medical oversight or medical supervision only. Attend regular tests and follow-ups to monitor the medicine response and reduce side effects. Before making any adjustments, changing the dose, or stopping the treatment, consult with your doctor to maximize the benefit.

Prostate Cancer

Side effects caused by the Bicatero 50mg Tablet (Bicalutamide) are normal, just like any other medicine. Consult the doctor if these symptoms worsen:

● Nausea

● Peripheral edema

● Breathlessness

● Enlargement of breasts

● Anemia

● Dizziness

● Weakness

● Weight gain

● Indigestion

● Hair loss

● Low appetite

● Low sex drive

● Blood glucose problem

Bicalutamide 50mg tablet (Bicatero) should be taken at the same time every day with or without food.

Swallow the tablet whole with water; do not crush or break it. Follow the doctor's guidance as recommended by the healthcare professional.

● Cockshott, I. D. (2004). Bicalutamide: clinical pharmacokinetics and metabolism. Clinical pharmacokinetics, 43(13), 855-878.

● Kolvenbag, G. J., Blackledge, G. R., & Gotting‐Smith, K. (1998). Bicalutamide (Casodex®) in the treatment of prostate cancer: history of clinical development. The Prostate, 34(1), 61-72.

● Kolvenbag, G. J., & Blackledge, G. R. (1996). Worldwide activity and safety of bicalutamide: a summary review. Urology, 47(1), 70-79.

● Furr, B. J. A., & Tucker, H. (1996). The preclinical development of bicalutamide: pharmacodynamics and mechanism of action. Urology, 47(1), 13-25.

● Osguthorpe, D. J., & Hagler, A. T. (2011). Mechanism of androgen receptor antagonism by bicalutamide in the treatment of prostate cancer. Biochemistry, 50(19), 4105-4113.​