Azalpho 100mg Injection (Azacitidine lyophilized)
Prescription RequiredManufactured By
Arechar Healthcare
Pack Of
1
Salt Composition
Azacitidine lyophilized
Storage
Keep in cold place
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Overview
Azalpho 100mg Injection is a prescription-based anticancer medicine used in the treatment of blood cancer and all subtypes of myelodysplastic syndrome (MDS), chronic myelomonocytic leukemia (CMML), and acute myeloid leukemia (AML). The active ingredient of Azalpho is azacitidine, which belongs to the drug class of antimetabolites. It works by damaging the genetic material (DNA and RNA) of the cancer cells, which stops their growth and helps to restore more normal blood cell production. An azacitidine 100mg injection is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
The injection is administered as a subcutaneous injection or an intravenous infusion by a qualified doctor in a hospital or clinical setting. This is supplied as a lyophilized powder that must be properly reconstituted before administration. The doctor determines the dosage of the Azacitidine 100mg injection according to the type of cancer, treatment regimen, age, and overall health of the patient. It should not be self-administered. Patients are advised not to change the dosage and timings prescribed by the doctors because it can cause severe side effects.
Common side effects include nausea, vomiting, diarrhea or constipation, tiredness, weakness, loss of appetite, fever, injection-site reactions, and headache. A few patients can undergo severe side effects, including severe infections, significant bleeding, allergic reactions, and kidney problems. Most of the Azacitidine 100mg injection side effects can leave when the body adapts to the medicine. However, if any side effects persist, inform your doctor immediately.
Regular blood tests are generally required to monitor blood counts and organ function during therapy. Patients must list all medicines, supplements, and herbal products that they are taking. The azacitidine 100mg injection must be used under medical oversight or medical supervision only. Attend regular tests and follow-ups to monitor the medicine response and reduce side effects. Before making any adjustments, changing the dose, or stopping the treatment, consult with your doctor to maximize the benefit.
Indication
Blood Cancer
Side Effects
The human body shows undesired symptoms after taking Azacitidine 100mg Injection (Azalpho). Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Common Side Effects
- Some of the common side effects of Azalpho Injection are mentioned below:
- ● Chills
- ● Fever
- ● Diarrhea
- ● Joint pain
- ● Headache
- ● Constipation
- ● Stomach Pain
- ● Nausea & Vomiting
- ● Bruising & Bleeding
- ● Low level of Potassium in the blood
- ● Pain and reaction at the injection site
- ● Decreased blood level (WBC, RBC, & Platelets)
Serious Side Effects
- ● Pneumonia
- ● Severe skin inflammation
- ● Frequent and painful urination
How To Use
Azacitidine 100mg Injection (Azalpho) is a prescription-based anticancer drug. It is advised to take this injection after consulting your healthcare expert. This medicine should be given intravenously by an experienced nurse or doctor. Please do not self-administer.
Reference
● Götze, K. S., Müller-Thomas, C., & Peschel, C. (2009). The role of azacitidine in the management of myelodysplastic syndromes (MDS). Cancer Management and Research, 119-130.
● Khan, C., Pathe, N., Fazal, S., Lister, J., & Rossetti, J. M. (2012). Azacitidine in the management of patients with myelodysplastic syndromes. Therapeutic advances in hematology, 3(6), 355-373.
● Silverman, L. R., Demakos, E. P., Peterson, B. L., Kornblith, A. B., Holland, J. C., Odchimar-Reissig, R., ... & Holland, J. F. (2002). Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B. Journal of Clinical oncology, 20(10), 2429-2440.
● Khan, C., Pathe, N., Fazal, S., Lister, J., & Rossetti, J. M. (2012). Azacitidine in the management of patients with myelodysplastic syndromes. Therapeutic advances in hematology, 3(6), 355-373.
● Kaminskas, E., Farrell, A., Abraham, S., Baird, A., Hsieh, L. S., Lee, S. L., ... & Pazdur, R. (2005). Approval summary: azacitidine for treatment of myelodysplastic syndrome subtypes. Clinical cancer research, 11(10), 3604-3608.
● Issa, J. P. J., Kantarjian, H. M., & Kirkpatrick, P. (2005). Azacitidine. Nature Reviews Drug Discovery, 4(4), 275-276.
Safety Advice
- ● Alcohol: The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Azalpho 100mg Injection (Azacitidine). It is advised to consult your doctor for further information.
- ● Pregnancy: Azacitidine 100mg Injection (Azalpho) may be considered unsafe during pregnancy. Please consult your doctor in such condition.
- ● Breastfeeding: Azalpho 100mg Injection (Azacitidine) is probably not safe if you're breastfeeding. Kindly consult your doctor.
- ● Driving: It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Azacitidine 100mg Injection (Azalpho).
- ● Kidney: Share your medical history with your healthcare expert in case of kidney disease before taking Azalpho 100mg Injection (Azacitidine).
- ● Liver: Inform your doctor before starting Azalpho 100mg Injection (Azacitidine) if you have liver disease to avoid any serious side effects.
FAQs
Does Azalpho Injection cause blisters?
No, Azalpho is not a vesicant and does not cause any irritation or blisters on contact.
Is Azacitidine 100mg Injection (Azalpho) toxic?
Yes, Azacitidine 100mg Injection is a cytotoxic drug. So, consult your doctor before taking this injection.
What are the dosage and usage of Azalpho 100mg Injection (Azacitidine)?
Your doctor will decide the dose and duration of taking this injection. It is strictly advised to follow the doctor's prescription. You need an expert nurse to inject into your veins. Do not self-administer it.
What type of drug is Azacitidine 100mg Injection (Azalpho)?
Azacitidine Injection is a chemotherapy drug that treats multiple cancers, including Blood cancer and Myelodysplastic syndrome.
Why is it important to use contraceptive pills while on treatment of Azalpho 100mg Injection (Azacitidine)?
Azalpho 100mg injection can pass through semen, so it is considered unsafe to be pregnant during treatment. It is advised to use reliable methods of birth control and contraceptive pills to avoid pregnancy while under treatment.
Marketer Details
Arechar Healthcare
Author Details
Written By:
Nonish Sharma
I am a medical content writer with a strong academic background in life sciences, holding an M.Sc. in Biotechnology... Read More
Reviewed By:
Vaibhav Shakya
Dr. Vaibhav Shakya, MD, is a Medical reviewer and medicine expert at Globans Pharma, with more than 9 years of experienc... Read More
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